Sargeant Harry William, Farrow Luke, Barker Scott, Kumar Kapil
Trauma and Orthopaedic Department, Aberden Royal Infirmary, Aberdeen, UK.
School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.
Shoulder Elbow. 2020 Aug;12(4):229-242. doi: 10.1177/1758573218825477. Epub 2019 Feb 2.
Humeral shaft fractures are common but debate still occurs as to whether these are best managed operatively or non-operatively. We sought to undertake a systematic review and meta-analysis of randomised and non-randomised studies to clarify the optimal treatment.
We performed a search for all randomised and non-randomised comparative studies on humeral shaft fracture. We included only those with an operative and non-operative cohort in adult patients. We undertook a meta-analysis of the following outcome measures: nonunion, malunion, delayed union, iatrogenic nerve injury and infection. Non-operative management was with a functional brace.
Non-operative management resulted in a significantly higher nonunion rate of 17.6% compared to 6.3% with fixation. Operative management had a significantly higher iatrogenic nerve injury rate of 3.4% and infection rate of 3.7%. All nonunions within the included studies went on to union after plate fixation. There was no significant difference in delayed union or patient reported outcome measures. There was a significantly increased risk of malunion with non-operative treatment however this did not correlate with the outcome.
Our findings suggest that in the majority of cases, humeral shaft fractures can be managed with non-operative treatment, and any subsequent nonunion should be treated with plate fixation.
肱骨干骨折很常见,但对于其最佳治疗方式是手术治疗还是非手术治疗仍存在争议。我们试图对随机和非随机研究进行系统评价和荟萃分析,以明确最佳治疗方法。
我们检索了所有关于肱骨干骨折的随机和非随机对照研究。仅纳入成年患者中设有手术组和非手术组的研究。我们对以下结局指标进行了荟萃分析:骨不连、畸形愈合、延迟愈合、医源性神经损伤和感染。非手术治疗采用功能性支具。
与固定治疗的6.3%相比,非手术治疗导致骨不连发生率显著更高,为17.6%。手术治疗的医源性神经损伤率显著更高,为3.4%,感染率为3.7%。纳入研究中的所有骨不连在钢板固定后均实现了愈合。延迟愈合或患者报告的结局指标方面无显著差异。然而,非手术治疗导致畸形愈合的风险显著增加,但这与结局无关。
我们的研究结果表明,在大多数情况下,肱骨干骨折可以采用非手术治疗,任何后续的骨不连都应采用钢板固定治疗。