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肱骨干骨折的手术治疗与非手术治疗:一项系统评价。

Operative versus non-operative treatment of humeral shaft fractures: A systematic review.

作者信息

Sargeant Harry William, Farrow Luke, Barker Scott, Kumar Kapil

机构信息

Trauma and Orthopaedic Department, Aberden Royal Infirmary, Aberdeen, UK.

School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.

出版信息

Shoulder Elbow. 2020 Aug;12(4):229-242. doi: 10.1177/1758573218825477. Epub 2019 Feb 2.

Abstract

BACKGROUND

Humeral shaft fractures are common but debate still occurs as to whether these are best managed operatively or non-operatively. We sought to undertake a systematic review and meta-analysis of randomised and non-randomised studies to clarify the optimal treatment.

METHODS

We performed a search for all randomised and non-randomised comparative studies on humeral shaft fracture. We included only those with an operative and non-operative cohort in adult patients. We undertook a meta-analysis of the following outcome measures: nonunion, malunion, delayed union, iatrogenic nerve injury and infection. Non-operative management was with a functional brace.

RESULTS

Non-operative management resulted in a significantly higher nonunion rate of 17.6% compared to 6.3% with fixation. Operative management had a significantly higher iatrogenic nerve injury rate of 3.4% and infection rate of 3.7%. All nonunions within the included studies went on to union after plate fixation. There was no significant difference in delayed union or patient reported outcome measures. There was a significantly increased risk of malunion with non-operative treatment however this did not correlate with the outcome.

DISCUSSION

Our findings suggest that in the majority of cases, humeral shaft fractures can be managed with non-operative treatment, and any subsequent nonunion should be treated with plate fixation.

摘要

背景

肱骨干骨折很常见,但对于其最佳治疗方式是手术治疗还是非手术治疗仍存在争议。我们试图对随机和非随机研究进行系统评价和荟萃分析,以明确最佳治疗方法。

方法

我们检索了所有关于肱骨干骨折的随机和非随机对照研究。仅纳入成年患者中设有手术组和非手术组的研究。我们对以下结局指标进行了荟萃分析:骨不连、畸形愈合、延迟愈合、医源性神经损伤和感染。非手术治疗采用功能性支具。

结果

与固定治疗的6.3%相比,非手术治疗导致骨不连发生率显著更高,为17.6%。手术治疗的医源性神经损伤率显著更高,为3.4%,感染率为3.7%。纳入研究中的所有骨不连在钢板固定后均实现了愈合。延迟愈合或患者报告的结局指标方面无显著差异。然而,非手术治疗导致畸形愈合的风险显著增加,但这与结局无关。

讨论

我们的研究结果表明,在大多数情况下,肱骨干骨折可以采用非手术治疗,任何后续的骨不连都应采用钢板固定治疗。

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本文引用的文献

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Humeral shaft fractures: union outcomes in a large cohort.肱骨干骨折:大型队列的愈合结局。
J Shoulder Elbow Surg. 2017 Nov;26(11):1881-1888. doi: 10.1016/j.jse.2017.07.001.
7
Nonoperative treatment of humeral shaft fractures revisited.肱骨干骨折的非手术治疗再探讨。
J Shoulder Elbow Surg. 2015 Feb;24(2):210-4. doi: 10.1016/j.jse.2014.05.009. Epub 2014 Aug 1.

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