[Evaluation of the cancer risk of intrauterine contraception based on cytological studies of the endometrium].

Risk for malignant transformation of the endometrium as a result of administration of intrauterine contraceptives for not more than 12 years was assessed by analysis of the mitotic cycle characteristics and sex chromatin level in the endometrium. No signs of pronounced proliferative processes or atypia were detected in the endometrium of females who took intrauterine contraceptives. However, a slight increase in metaphases and pathologic mitoses was observed in those women who had used contraceptives for a period longer than 7 years.