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特发性三叉神经痛的包裹技术:病例系列

Wrap technique for idiopathic trigeminal neuralgia: patient series.

作者信息

Koh Sophie Jia Qian, Kumar A Aravin, Hwang Peter Ying Khai

机构信息

Department of Neurosurgery, National Neuroscience Institute, Singapore.

出版信息

J Neurosurg Case Lessons. 2025 Aug 18;10(7). doi: 10.3171/CASE25348.

DOI:10.3171/CASE25348
PMID:40825252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12362195/
Abstract

BACKGROUND

Idiopathic trigeminal neuralgia (TN) presents significant diagnostic and therapeutic challenges. While microvascular decompression (MVD) is well established for classic TN, its role in idiopathic cases remains controversial due to the absence of an identifiable neurovascular conflict and lack of clear anatomical target. New strategies are needed to address this challenging patient population.

OBSERVATIONS

Six patients with idiopathic TN underwent MVD with a Teflon wrap placed around the trigeminal nerve. All had undergone high-resolution MRI (CISS or FIESTA sequence), and intraoperative exploration was negative for a neurovascular conflict. Intraoperative trigeminal-hypoglossal reflex (THR) monitoring was used as a functional marker of decompression. All patients exhibited intact THR at baseline and complete loss of THR after wrap placement, indicating adequate decompression. Preoperative Barrow Neurological Institute pain scores (BNI-PSs) ranged from III to V. Five patients achieved sustained pain relief (BNI-PS of 0 or I) by postoperative day 1. One patient experienced delayed improvement but progressed from BNI-PS IV to 0 by 6 months. All patients remained pain free at 18 months.

LESSONS

A Teflon wrap technique with intraoperative THR monitoring may represent a safe and effective surgical option for idiopathic TN. By addressing potential biomechanical or dynamic nerve dysfunction, this approach offers meaningful pain relief even in the absence of a visible vascular conflict. https://thejns.org/doi/10.3171/CASE25348.

摘要

背景

特发性三叉神经痛(TN)在诊断和治疗方面存在重大挑战。虽然微血管减压术(MVD)在经典TN中已得到广泛应用,但其在特发性病例中的作用仍存在争议,因为缺乏可识别的神经血管冲突且解剖靶点不明确。需要新的策略来应对这一具有挑战性的患者群体。

观察结果

6例特发性TN患者接受了MVD,术中在三叉神经周围放置了聚四氟乙烯包裹物。所有患者均接受了高分辨率MRI(CISS或FIESTA序列)检查,术中探查未发现神经血管冲突。术中使用三叉神经 - 舌下神经反射(THR)监测作为减压的功能指标。所有患者在基线时THR均完整,包裹物放置后THR完全消失,表明减压充分。术前巴罗神经学研究所疼痛评分(BNI - PS)范围为III至V级。5例患者在术后第1天实现了持续疼痛缓解(BNI - PS为0或I级)。1例患者改善延迟,但在6个月时从BNI - PS IV级进展至0级。所有患者在18个月时均无疼痛。

经验教训

术中进行THR监测的聚四氟乙烯包裹技术可能是特发性TN一种安全有效的手术选择。通过解决潜在的生物力学或动态神经功能障碍,即使在没有明显血管冲突的情况下,这种方法也能提供有意义的疼痛缓解。https://thejns.org/doi/10.3171/CASE25348

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb17/12362195/5b0238a5af1a/CASE25348_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb17/12362195/5b0238a5af1a/CASE25348_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb17/12362195/5b0238a5af1a/CASE25348_figure_1.jpg

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