Kantanen Juha, Weldenegodguad Melak, Pokharel Kisun
Natural Resources Institute Finland, Tietotie 4, Jokioinen, 31600, Finland.
Natural Resources Institute Finland, Latokartanonkaari 9, Helsinki, 00790, Finland.
BMC Genom Data. 2025 Aug 19;26(1):59. doi: 10.1186/s12863-025-01354-x.
Finnsheep, a highly prolific breed of sheep, has been globally exported for improving fertility traits of many sheep breeds. Published genomic studies of Finnsheep have been based on Texel and Rambouillet reference genomes, which may not capture its unique genetic features. Our main objective was to generate a high-quality Finnsheep genome assembly and its annotation that could serve as a breed-specific reference for studying fertility and adaptation in Finnsheep and other short-tailed northern European sheep breeds.
We generated a 2.53 Gb assembly using PacBio HiFi long-reads and Hi-C sequencing from a highly fertile Finnsheep ewe. The assembly, scaffolded with Hi-C data has a contig N50 of 35.5 Mb and scaffold N50 of 100.6 Mb. Gene annotation identified 42,533 genes spanning 46.5 Mb of coding region. BUSCO completeness for the assembly and annotation was 94.9% and 84.3%, respectively. This data, including raw reads, assembly, and annotations supports genomic studies of Finnsheep and other prolific breeds of sheep that are particularly adapted to northern European environments.
芬兰羊是一种繁殖力高的绵羊品种，已在全球范围内出口，用于改善许多绵羊品种的繁殖性状。已发表的芬兰羊基因组研究基于特克塞尔羊和兰布列羊的参考基因组，这可能无法捕捉到其独特的遗传特征。我们的主要目标是生成一个高质量的芬兰羊基因组组装及其注释，作为研究芬兰羊和其他北欧短尾绵羊品种繁殖力和适应性的特定品种参考。
我们使用来自一只高繁殖力芬兰母羊的PacBio HiFi长读长测序和Hi-C测序生成了一个2.53 Gb的组装。用Hi-C数据进行支架构建后的组装，其重叠群N50为35.5 Mb，支架N50为100.6 Mb。基因注释鉴定出42533个基因，跨越46.5 Mb的编码区域。该组装和注释的BUSCO完整性分别为94.9%和84.3%。这些数据，包括原始读数、组装和注释，支持对芬兰羊和其他特别适应北欧环境的多产绵羊品种的基因组研究。
