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2010 - 2021年加利福尼亚州娱乐用大麻合法化与大麻使用障碍治疗结果之间的关联

Associations between recreational cannabis legalization and cannabis use disorder treatment outcomes in California, 2010-2021.

作者信息

Bass Brittany, Padwa Howard, Khurana Dhruv, Urada Darren

机构信息

Department of Addiction Psychiatry, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, 10911 Weyburn Avenue, Suite 200, Los Angeles, CA, 90024, USA.

出版信息

J Cannabis Res. 2025 Aug 18;7(1):60. doi: 10.1186/s42238-025-00323-6.

Abstract

BACKGROUND

Despite extensive research on the broader effects of recreational cannabis legalization (RCL), limited attention has been given to its impact on cannabis use disorder (CUD) treatment outcomes. This study addresses this gap by analyzing CUD treatment outcomes, including 90-day treatment retention and successful discharge.

METHODS

Data were collected from a dataset of all publicly funded cannabis use disorder treatment delivered in California between January 2010 and December 2021 ( = 192,580). RCL’s impacts on CUD treatment outcomes was estimated using an individual-level pre-post time series model, including individual and county-level characteristics via logistic regression.

RESULTS

California’s RCL was associated with a significant decrease in the probability of 90-day treatment retention and also of successful discharge from treatment for patients with a CUD. RCL was also associated with a decrease in the probability of 90-day CUD treatment retention for adults ages 21 + and White Non-Hispanics, and a decrease in the probability of successful discharge for White Non-Hispanics, and an increase in the probability of successful discharge for males and adults ages 21+. We find no association between RCL and treatment retention or successful discharge for Black Non-Hispanic or Hispanic patients.

CONCLUSIONS

The implementation of California’s RCL was associated with a decline in CUD treatment outcomes. The findings underscore the need for ongoing evaluation of cannabis legalization’s effects on public health to inform policy and practice in the context of evolving cannabis regulations.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1186/s42238-025-00323-6.

摘要

背景

尽管对娱乐用大麻合法化(RCL)的广泛影响进行了大量研究,但对其对大麻使用障碍(CUD)治疗结果的影响关注有限。本研究通过分析CUD治疗结果,包括90天治疗保留率和成功出院情况,来填补这一空白。

方法

数据收集自2010年1月至2021年12月在加利福尼亚州提供的所有公共资助的大麻使用障碍治疗数据集(n = 192,580)。使用个体水平的前后时间序列模型估计RCL对CUD治疗结果的影响,通过逻辑回归纳入个体和县级特征。

结果

加利福尼亚州的RCL与CUD患者90天治疗保留率以及成功出院概率的显著降低相关。RCL还与21岁及以上成年人和非西班牙裔白人90天CUD治疗保留率的降低、非西班牙裔白人成功出院概率的降低以及男性和21岁及以上成年人成功出院概率的增加相关。我们发现RCL与非西班牙裔黑人或西班牙裔患者的治疗保留率或成功出院之间没有关联。

结论

加利福尼亚州RCL的实施与CUD治疗结果的下降相关。这些发现强调了持续评估大麻合法化对公共卫生影响的必要性,以便在不断演变的大麻法规背景下为政策和实践提供信息。

补充信息

在线版本包含可在10.1186/s42238-025-00323-6获取的补充材料。

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