Comparative Outcomes of Open Simple Prostatectomy in Men with or Without Prior History of Transurethral Resection of the Prostate.

Objective: This retrospective cross-sectional study aimed to compare functional and surgical outcomes after open simple prostatectomy (OSP) between patients who underwent prior transurethral resection of the prostate (TURP) and those who did not. Methods: Between March 2009 and April 2019, 723 patients underwent TURP, of whom 20 (2.7%) subsequently underwent OSP (Group 1). This group was matched with a group of patients who had solely undergone OSP (Group 2), with matching criteria including age, prostate-specific antigen level, prostate volume, and prostate weight. Results: Group 1 showed a statistically significant lower decrease in hemoglobin levels after surgery (p = .006); however, no significant differences were observed between the groups in terms of operation time (P=.508), hospital stay (P=.065), transfusion rate (P=.331), enucleated prostate volume (P=.733), or changes in creatinine levels (P =.418). Regarding early postoperative complications, the 2 groups showed no significant difference (0.349). Late postoperative complications occurred in 30% of Group 1 and 33% of Group 2, which was not significantly different either (P = .241). Both groups achieved similar early continence rates (88%) within the first 6 months after surgery. Late continence rates (after 6 months) were also comparable, with 94% in Group 1 and 88% in Group 2. Finally, no significant differences were found in patient satisfaction levels, measured on a qualitative scale ranging from "dissatisfied" to "highly satisfied." Conclusion: Prior TURP did not significantly affect the surgical or functional outcomes of subsequent OSP, with comparable results observed between patients with and with- out a history of TURP.