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[掌腱膜纤维瘤病(杜普伊特伦病)细胞的增殖与3H脯氨酸掺入]

[Proliferation and 3H proline incorporation of cells of palmar fibromatosis (Dupuytren disease)].

作者信息

Mohr W, Vossbeck G

出版信息

Z Rheumatol. 1985 Sep-Oct;44(5):226-30.

PMID:4082789
Abstract

Proliferation and 3H-proline incorporation were studied autoradiographically in cells of Dupuytren's fibromatosis. It was observed that cells in the fibromatous tissue only exhibit a minimal proliferation rate. Increased 3H-thymidine labelling was found in vascular and perivascular cells. The finding may indicate that cells of perivascular areas contribute to the formation of the nodules. 3H-proline labelling was pronounced over cells of the fibromatous tissue leading to the assumption that these cells are highly metabolic.

摘要

在掌腱膜纤维瘤病的细胞中,通过放射自显影术研究了细胞增殖和3H-脯氨酸掺入情况。观察到纤维瘤组织中的细胞仅表现出极低的增殖率。在血管和血管周围细胞中发现3H-胸腺嘧啶核苷标记增加。这一发现可能表明血管周围区域的细胞对结节的形成有贡献。在纤维瘤组织的细胞上3H-脯氨酸标记明显,这导致人们认为这些细胞具有高代谢活性。

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