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Pharmacological Strategies for the Treatment of Restless Legs Syndrome.

作者信息

Anguizola David, Garcia Aragón Alba, Lopez Jimenez Alejandro, Sainz Valentin, Garcia-Borreguero Diego

机构信息

Instituto Europeo del Sueño, Panama City, Panamá.

Sleep Research Institute, Madrid, Spain.

出版信息

Curr Neurol Neurosci Rep. 2025 Aug 19;25(1):60. doi: 10.1007/s11910-025-01445-3.

DOI:10.1007/s11910-025-01445-3
PMID:40828344
Abstract
摘要

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Pharmacological Strategies for the Treatment of Restless Legs Syndrome.治疗不宁腿综合征的药理学策略
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2
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本文引用的文献

1
Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline.不宁腿综合征和周期性肢体运动障碍的治疗：美国睡眠医学学会临床实践指南
J Clin Sleep Med. 2025 Jan 1;21(1):137-152. doi: 10.5664/jcsm.11390.
2
Efficacy and safety of TOMAC for treatment of medication-naïve and medication-refractory restless legs syndrome: A randomized clinical trial and meta-analysis.TOMAC 治疗未经药物治疗和药物难治性不安腿综合征的疗效和安全性：一项随机临床试验和荟萃分析。
Sleep Med. 2024 Oct;122:141-148. doi: 10.1016/j.sleep.2024.08.017. Epub 2024 Aug 18.
3
Association of low serum ferritin levels with augmentation in patients with restless legs syndrome: A systematic review and meta-analysis.
低血清铁蛋白水平与不宁腿综合征患者增龄的相关性：系统评价和荟萃分析。
Sleep Med. 2023 Dec;112:173-180. doi: 10.1016/j.sleep.2023.10.022. Epub 2023 Oct 20.
4
Worldwide estimation of restless legs syndrome: a systematic review and meta-analysis of prevalence in the general adult population.全球不宁腿综合征的评估：对普通成年人群患病率的系统评价和荟萃分析。
J Sleep Res. 2023 Jun;32(3):e13783. doi: 10.1111/jsr.13783. Epub 2023 Jan 4.
5
Presynaptic adenosine receptor heteromers as key modulators of glutamatergic and dopaminergic neurotransmission in the striatum.突触前腺苷受体异聚体作为纹状体中谷氨酸能和多巴胺能神经传递的关键调节因子。
Neuropharmacology. 2023 Feb 1;223:109329. doi: 10.1016/j.neuropharm.2022.109329. Epub 2022 Nov 11.
6
Restless legs syndrome.不宁腿综合征。
Nat Rev Dis Primers. 2021 Nov 3;7(1):80. doi: 10.1038/s41572-021-00311-z.
7
Correlation between systemic iron parameters and substantia nigra iron stores in restless legs syndrome.不宁腿综合征患者的系统性铁参数与黑质铁储存量之间的相关性。
Sleep Med. 2021 Sep;85:191-195. doi: 10.1016/j.sleep.2021.07.027. Epub 2021 Jul 21.
8
The Long-Term Psychiatric and Cardiovascular Morbidity and Mortality of Restless Legs Syndrome and Periodic Limb Movements of Sleep.不宁腿综合征和睡眠周期性肢体运动的长期精神和心血管发病率和死亡率。
Sleep Med Clin. 2021 Jun;16(2):279-288. doi: 10.1016/j.jsmc.2021.02.005. Epub 2021 Apr 15.
9
Restless Legs Syndrome: Challenges to Treatment.不宁腿综合征：治疗面临的挑战
Sleep Med Clin. 2021 Jun;16(2):269-277. doi: 10.1016/j.jsmc.2021.02.003. Epub 2021 Apr 15.
10
Restless Legs Syndrome: Contemporary Diagnosis and Treatment.不宁腿综合征：当代诊断与治疗。
Neurotherapeutics. 2021 Jan;18(1):140-155. doi: 10.1007/s13311-021-01019-4. Epub 2021 Apr 20.