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优化孟加拉国科克斯巴扎尔罗兴亚难民中的丙型肝炎病毒管理:应对辅助因素和环境风险以减轻长期肝病并发症

Optimizing HCV Management Among Rohingya Refugees in Cox's Bazar, Bangladesh: Addressing Cofactors and Environmental Risks to Mitigate Long-Term Liver Disease Complications.

作者信息

Ceccarelli Giancarlo, Branda Francesco, Fairouz Fariha, Albanese Mattia, Scarpa Fabio, Ciccozzi Massimo

机构信息

Sapienza University of Rome, Rome, Italy.

Università Campus Bio-Medico, Rome, Italy.

出版信息

J Immigr Minor Health. 2025 Aug 19. doi: 10.1007/s10903-025-01751-5.

Abstract

Hepatitis C virus (HCV) infection is increasingly reported among Rohingya refugees in Cox's Bazar, with active infection rates in adults reaching 20% by 2023. The risk of liver disease progression and hepatocellular carcinoma (HCC) may be amplified by coexisting factors such as chronic malnutrition, coinfections, aflatoxin exposure, metabolic disorders, and environmental toxins. Despite WHO-led efforts, data on these risk factors remain fragmented, and access to care is limited. This study underscores the need for comprehensive surveillance, epidemiological research, and long-term prevention strategies to reduce HCV-related morbidity and the future burden of HCC in displaced Rohingya populations.

摘要

在科克斯巴扎尔的罗兴亚难民中,丙型肝炎病毒(HCV)感染的报告越来越多,到2023年,成年人中的活动性感染率达到20%。慢性营养不良、合并感染、黄曲霉毒素暴露、代谢紊乱和环境毒素等共存因素可能会加剧肝病进展和肝细胞癌(HCC)的风险。尽管世界卫生组织牵头开展了相关工作,但关于这些风险因素的数据仍然零散,获得医疗服务的机会也有限。这项研究强调了开展全面监测、流行病学研究以及制定长期预防策略的必要性,以降低流离失所的罗兴亚人群中与HCV相关的发病率以及未来HCC的负担。

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