Grabe N, Jakobsen C J, Damm M D
Acta Anaesthesiol Scand. 1985 Nov;29(8):764-6. doi: 10.1111/j.1399-6576.1985.tb02297.x.
A prospective randomized study evaluating the effects of skin disinfectants before intravenous cannulation was undertaken. 187 intravenous cannulae were examined. Patients were divided into two groups: in one, 70% isopropyl alcohol was used as a skin disinfectant while in the other, no skin disinfectant was used. Intraluminal contamination rates, colony counts and organisms isolated were analysed. No significant differences were found between the two groups. There was no correlation between the use of the sideport and contamination. It appears, therefore, that 70% isopropyl alcohol cannot prevent or even reduce the intraluminal contamination.
开展了一项前瞻性随机研究，以评估静脉插管前皮肤消毒剂的效果。共检查了187根静脉插管。患者被分为两组：一组使用70%异丙醇作为皮肤消毒剂，另一组不使用皮肤消毒剂。分析了管腔内污染率、菌落计数和分离出的微生物。两组之间未发现显著差异。侧孔的使用与污染之间没有相关性。因此，看来70%异丙醇不能预防甚至降低管腔内污染。
