• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项关于外科手术患者静脉穿刺前使用异丙醇擦拭效果的前瞻性对照试验。

A prospective controlled trial of the efficacy of isopropyl alcohol wipes before venesection in surgical patients.

作者信息

Sutton C D, White S A, Edwards R, Lewis M H

机构信息

Department of Surgery, Leicester General Hospital, UK.

出版信息

Ann R Coll Surg Engl. 1999 May;81(3):183-6.

PMID:10364951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2503183/
Abstract

It has previously been suggested that skin preparation before venesection with antiseptic agents is unnecessary. However thousands of doctors and medical students continue to use isopropyl alcohol (IPA) swabs for venesection, at an estimated cost of 10,000 P per annum in a 500 bed hospital. An audit of IPA swab use among junior doctors and medical students at our institution was undertaken; 76% of doctors and 100% of medical students routinely prepared the skin with alcohol before venesection and only one used the swabs correctly. A randomised single-blind controlled trial was conducted of IPA versus no IPA skin preparation before venesection. There were 194 patients in the study, 93 in the IPA group and 101 controls. There was no statistical difference with respect to complications at the venepuncture site between the two groups.

摘要

此前有人提出,静脉切开术前用抗菌剂进行皮肤准备是不必要的。然而,成千上万的医生和医学生仍继续使用异丙醇(IPA)棉签进行静脉切开术,在一家拥有500张床位的医院,估计每年花费10000菲律宾比索。我们对本机构的初级医生和医学生使用IPA棉签的情况进行了一次审核;76%的医生和100%的医学生在静脉切开术前常规用酒精进行皮肤准备,只有一人正确使用了棉签。对静脉切开术前使用IPA与不使用IPA进行皮肤准备进行了一项随机单盲对照试验。该研究有194名患者,IPA组93名,对照组101名。两组在静脉穿刺部位的并发症方面无统计学差异。

相似文献

1
A prospective controlled trial of the efficacy of isopropyl alcohol wipes before venesection in surgical patients.一项关于外科手术患者静脉穿刺前使用异丙醇擦拭效果的前瞻性对照试验。
Ann R Coll Surg Engl. 1999 May;81(3):183-6.
2
Reducing Mediastinitis after Sternotomy with Combined Chlorhexidine-Isopropyl Alcohol Skin Disinfection: Analysis of 3,000 Patients.联合洗必泰-异丙醇皮肤消毒降低胸骨切开术后纵隔炎:3000例患者分析
Surg Infect (Larchmt). 2016 Oct;17(5):552-6. doi: 10.1089/sur.2015.140. Epub 2016 Jun 9.
3
Skin antisepsis kits containing alcohol and chlorhexidine gluconate or tincture of iodine are associated with low rates of blood culture contamination.含有酒精、葡萄糖酸氯己定或碘酊的皮肤消毒套装与较低的血培养污染率相关。
Infect Control Hosp Epidemiol. 2002 Jul;23(7):397-401. doi: 10.1086/502073.
4
Skin disinfection with octenidine dihydrochloride for central venous catheter site care: a double-blind, randomized, controlled trial.用奥替尼啶二盐酸盐对中央静脉置管部位进行皮肤消毒:一项双盲、随机、对照试验。
Clin Microbiol Infect. 2010 Jun;16(6):600-6. doi: 10.1111/j.1469-0691.2009.02917.x. Epub 2009 Aug 17.
5
Lack of effect on blood alcohol level of swabbing venepuncture sites with 70% isopropyl alcohol.用 70%异丙醇擦拭静脉穿刺部位对血液酒精水平没有影响。
Emerg Med Australas. 2010 Feb;22(1):9-12. doi: 10.1111/j.1742-6723.2009.01248.x. Epub 2009 Dec 8.
6
Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination.异丙醇与异丙醇加聚维酮碘作为预防血培养污染的皮肤准备剂的比较。
J Clin Microbiol. 2009 Jan;47(1):54-8. doi: 10.1128/JCM.01425-08. Epub 2008 Oct 29.
7
Preoperative skin preparation of the foot and ankle: bristles and alcohol are better.足部和踝部术前皮肤准备:用鬃刷和酒精效果更佳。
J Bone Joint Surg Am. 2005 May;87(5):986-92. doi: 10.2106/JBJS.D.02695.
8
Preoperative skin and nail preparation of the foot: comparison of the efficacy of 4 different methods in reducing bacterial load.足部术前皮肤和指甲准备:4种不同方法在降低细菌载量方面的疗效比较
J Am Acad Dermatol. 2009 Dec;61(6):986-92. doi: 10.1016/j.jaad.2009.04.045. Epub 2009 Aug 7.
9
The importance of isopropyl alcohol in skin preparation solutions.
Infect Control Hosp Epidemiol. 2011 Apr;32(4):405-6; author reply 406-8. doi: 10.1086/659254.
10
Efficacy of surgical preparation solutions in lumbar spine surgery.脊柱手术中外科准备溶液的疗效。
J Bone Joint Surg Am. 2012 Mar 21;94(6):490-4. doi: 10.2106/JBJS.K.00471.

引用本文的文献

1
Assessing the Efficacy of Alcohol Swabbing in Preventing Bacterial Colonization of Single-Use Vials: A Pilot Study.评估酒精擦拭在预防一次性药瓶细菌定植中的效果:一项初步研究。
Cureus. 2025 Aug 19;17(8):e90512. doi: 10.7759/cureus.90512. eCollection 2025 Aug.
2
The economics of global COVID vaccine administration during a pandemic - Why continue skin alcohol preparation as a costly but ineffective practice?大流行期间全球新冠疫苗接种的经济学——为何继续将皮肤酒精消毒作为一种成本高昂却无效的做法?
Vaccine. 2021 Feb 22;39(8):1175-1177. doi: 10.1016/j.vaccine.2020.12.082. Epub 2021 Jan 21.
3
Shoulder septic arthritis following routine influenza vaccination.常规流感疫苗接种后发生的肩部化脓性关节炎。
J Surg Case Rep. 2020 Dec 7;2020(12):rjaa458. doi: 10.1093/jscr/rjaa458. eCollection 2020 Dec.
4
Cellular reactions in capillary and venous blood in northerners to a short-term period in a climatic chamber.北方人在气候室内短期停留时的毛细血管和静脉血液中的细胞反应。
Immun Inflamm Dis. 2020 Sep;8(3):408-414. doi: 10.1002/iid3.322. Epub 2020 Jun 17.
5
Sepsis, parenteral vaccination and skin disinfection.脓毒症、肠胃外接种及皮肤消毒。
Hum Vaccin Immunother. 2016 Oct 2;12(10):2546-2559. doi: 10.1080/21645515.2016.1190489. Epub 2016 Jun 13.
6
Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion.使用酒精进行皮肤准备与先使用酒精再使用任何防腐剂预防菌血症或输血时血液污染的比较。
Cochrane Database Syst Rev. 2015 Feb 12;2015(2):CD007948. doi: 10.1002/14651858.CD007948.pub3.

本文引用的文献

1
METHODS FOR DISINFECTION OF HANDS AND OPERATION SITES.手部及手术部位的消毒方法
Br Med J. 1964 Aug 29;2(5408):531-6. doi: 10.1136/bmj.2.5408.531.
2
The virulence of Staphylococcus pyogenes for man; a study of the problems of wound infection.酿脓链球菌对人类的毒力;伤口感染问题研究
Br J Exp Pathol. 1957 Dec;38(6):573-86.
3
The effect of skin disinfection materials on reducing blood culture contamination.皮肤消毒材料对减少血培养污染的影响。
Am J Clin Pathol. 1993 May;99(5):536-8. doi: 10.1093/ajcp/99.5.536.
4
The bacterial flora of the antecubital fossa: the efficacy of alcohol disinfection of this site, the palm and the forehead.肘前窝的细菌菌群:该部位、手掌及前额酒精消毒的效果。
J Invest Dermatol. 1980 Aug;75(2):140-3. doi: 10.1111/1523-1747.ep12521658.
5
Use of 4 per cent chlorhexidine detergent solution (Hibiscrub) and other methods of skin disinfection.使用4%氯己定洗涤剂溶液(洗必泰醇)及其他皮肤消毒方法。
Br Med J. 1973 Mar 3;1(5852):510-5. doi: 10.1136/bmj.1.5852.510.
6
Preoperative disinfection of surgeons' hands: use of alcoholic solutions and effects of gloves on skin flora.外科医生手部的术前消毒:酒精溶液的使用及手套对皮肤菌群的影响。
Br Med J. 1974 Nov 16;4(5941):369-72. doi: 10.1136/bmj.4.5941.369.
7
Routine skin preparation before injection: an unnecessary procedure.注射前常规皮肤准备:一项不必要的操作。
Lancet. 1969 Jul 12;2(7611):96-8. doi: 10.1016/s0140-6736(69)92405-2.
8
Skin disinfection before intravenous cannulation. Intraluminal contamination after disinfection with 70% isopropyl alcohol.静脉插管前的皮肤消毒。用70%异丙醇消毒后管腔内污染。
Acta Anaesthesiol Scand. 1985 Nov;29(8):764-6. doi: 10.1111/j.1399-6576.1985.tb02297.x.
9
Contamination reduction during central venous catheterization.
Crit Care Med. 1988 Feb;16(2):165-7. doi: 10.1097/00003246-198802000-00014.
10
Guideline for use of topical antimicrobial agents.局部用抗菌药物使用指南。
Am J Infect Control. 1988 Dec;16(6):253-66. doi: 10.1016/s0196-6553(88)80005-1.