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在过去十年中,与腰椎退行性滑脱的器械辅助后外侧入路相比,非器械辅助后外侧腰椎融合术的应用持续减少。

Noninstrumented Posterolateral Lumbar Fusions Continue to Fade Relative to Instrumented Posterolateral Approaches for Lumbar Degenerative Spondylolisthesis Over the Past Decade.

作者信息

Lee Albert H, Day Wesley, Lavu Siddhartha, Pappajohn Alexandros F, Gouzoulis Michael J, Grauer Jonathan N

机构信息

From the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT (Mr. Lee, Mr. Lavu, Mr. Pappajohn, Mr. Gouzoulis, and Dr. Grauer), and the Albert Einstein College of Medicine, Bronx, NY (Mr. Day).

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2025 Aug 19;9(8). doi: 10.5435/JAAOSGlobal-D-25-00192. eCollection 2025 Aug 1.

Abstract

INTRODUCTION

Although posterolateral lumbar fusions (PLFs) were historically routinely performed without instrumentation, instrumentation has become ubiquitous in this setting. Recent assessments of noninstrumented PLFs practices are lacking.

METHODS

Lumbar degenerative spondylolisthesis patients undergoing noninstrumented or instrumented single-level PLFs (with or without interbody) were identified from 2012 to 2022 M170 Ortho PearlDiver. Univariable analysis identified differences in patient characteristics. Yearly utilization trends were tracked and analyzed using simple linear regression/overall F-tests. Ninety-day postoperative adverse outcomes were compared using multivariable logistic regression with 4:1 matching for patient age, sex, and Elixhauser comorbidity index. Five-year lumbar revision surgery rates were assessed using Kaplan-Meier survival analyses and log-rank tests.

RESULTS

A total of 117,796 (95.8%) instrumented and 5147 (4.2%) noninstrumented PLF lumbar degenerative spondylolisthesis patients were identified. Noninstrumented PLFs declined from 5.52% to 3.49% from 2012 to 2022 (P < 0.001). These were more common in older, male, osteoporotic patients, varied by insurance and region, and were more often performed by orthopaedic surgeons. After matching, no notable differences were found between instrumented versus noninstrumented cases in 90-day aggregated adverse events or 5-year lumbar revision surgery rates.

DISCUSSION

For lumbar degenerative spondylolisthesis, noninstrumented fusion represents a small and declining percentage of PLFs over the past decade, with usage varied by clinical and nonclinical patient characteristics. No differences were found in 90-day aggregated postoperative adverse events and 5-year lumbar revision surgery rates, suggesting that instrumentation can be safely performed and that both approaches had similarly durable results. These findings support considering noninstrumented PLFs in select cases when the safety, utility, or cost-benefit of instrumentation is questioned.

摘要

引言

尽管从历史上看,腰椎后外侧融合术(PLF)在常规实施时不使用内固定器械,但如今在这种手术中使用内固定器械已变得十分普遍。目前缺乏对非器械辅助PLF手术操作的最新评估。

方法

从2012年至2022年的M170 Ortho PearlDiver数据库中识别出接受非器械辅助或器械辅助单节段PLF(有或无椎间融合)的腰椎退行性椎体滑脱患者。单因素分析确定了患者特征的差异。使用简单线性回归/总体F检验跟踪和分析年度使用趋势。采用多因素逻辑回归对患者年龄、性别和埃利克斯豪泽合并症指数进行4:1匹配,比较术后90天不良结局。使用Kaplan-Meier生存分析和对数秩检验评估5年腰椎翻修手术率。

结果

共识别出117,796例(95.8%)接受器械辅助PLF的腰椎退行性椎体滑脱患者和5147例(4.2%)接受非器械辅助PLF 的患者。2012年至2022年期间,非器械辅助PLF的比例从5.52%降至3.49%(P < 0.001)。这些手术在年龄较大、男性、骨质疏松的患者中更为常见,因保险类型和地区而异,并且更多由骨科医生实施。匹配后,在术后90天的总体不良事件或5年腰椎翻修手术率方面,器械辅助与非器械辅助病例之间未发现显著差异。

讨论

对于腰椎退行性椎体滑脱,在过去十年中,非器械辅助融合术在PLF中所占比例较小且呈下降趋势,其使用因临床和非临床患者特征而异。在术后90天的总体不良事件和5年腰椎翻修手术率方面未发现差异,这表明使用内固定器械可以安全进行,并且两种方法的效果同样持久。这些发现支持在对使用内固定器械的安全性、实用性或成本效益存在疑问的特定情况下考虑非器械辅助PLF。

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