Yamanaka N, Somekawa Y, Kataura A
Acta Otolaryngol. 1985 Nov-Dec;100(5-6):399-404. doi: 10.3109/00016488509126563.
Spontaneous DNA synthesis (SDS) in adenoidal lymphocytes was investigated in 37 children with particular attention to the relationship between the adenoids and otitis media with effusion (OME). The SDS was measured by [3H]thymidine incorporation under a certain culture condition without any mitogens. Adenoidal lymphocytes showed an extremely higher uptake of [3H]thymidine than did peripheral lymphocytes. SDS in adenoidal lymphocytes was much greater in the 3-5-year-old age group than in the older groups. SDS in patients with OME was also significantly greater than that in patients with no complications. Patients who recovered from OME within 3 months following adenoidectomy showed significantly greater SDS than those with recurrent effusion over 6 months. These results might indicate a relationship between the adenoids and OME.
对37名儿童的腺样体淋巴细胞中的自发DNA合成（SDS）进行了研究，特别关注腺样体与分泌性中耳炎（OME）之间的关系。在无任何促有丝分裂原的特定培养条件下，通过[3H]胸腺嘧啶核苷掺入法测定SDS。腺样体淋巴细胞对[3H]胸腺嘧啶核苷的摄取比外周淋巴细胞高得多。3-5岁年龄组腺样体淋巴细胞中的SDS比年龄较大组的要大得多。OME患者的SDS也明显高于无并发症患者。腺样体切除术后3个月内从OME康复的患者的SDS明显高于积液复发超过6个月的患者。这些结果可能表明腺样体与OME之间存在关联。
