Eroğlu Fatma Elif, Orhan Gürdal, Arlı Berna, Hatipoğlu Hatice Gül, Sanlier Nevin
Department of Nutrition and Dietetics, Gülhane Health Sciences Faculty University of Health Sciences Ankara Turkey.
Ankara Bilkent City Hospital Ankara Turkey.
Food Sci Nutr. 2025 Aug 18;13(8):e70722. doi: 10.1002/fsn3.70722. eCollection 2025 Aug.
This study aims to evaluate the relationship between some serum parameters, the dietary inflammatory index (DII), quality of life, depression, and nutritional status in women diagnosed with multiple sclerosis (MS). A total of 153 women aged 20-50 residing in Ankara participated in the study, including 73 MS patients and 80 in the control group. The study assessed general characteristics, anthropometric measurements, the Multiple Sclerosis Quality of Life Scale (MSQOL-54), the Beck Depression Inventory-21 (BDI), MIND Diet Score (MIND), a 3-day food consumption record, the Healthy Eating Index-2015 (HEI-2015), DII, and biochemical findings. The average waist circumference in the MS group (84.5 ± 12.22 cm) was significantly higher than that of the control group (80.5 ± 10.60 cm) ( < 0.05). The average BDI score was 12.9 ± 9.66 points in the MS group and 7.9 ± 6.16 points in the control group, with the MS group scoring significantly higher ( < 0.05). The mean MIND diet score in the MS group (6.3 ± 1.90) was significantly lower ( < 0.05) compared to the control group (6.9 ± 1.71). The mean DII and HEI-2015 scores were lower in the control group (2.2 ± 2.34 and 44.6 ± 9.86, respectively) compared to the MS group (2.4 ± 2.43 and 44.8 ± 12.69). In the MS group, 64.2% had a poor diet, whereas 72.5% of the control group had a poor diet. In the control group, 27.5% had a diet needing improvement compared to 34.6% in the MS group. This study provides detailed insights into anthropometric measurements, serum parameters, depression, and especially nutritional status in MS patients. Given the significantly low MIND diet scores in individuals with MS, implementing individualized medical nutrition therapy would be beneficial. This approach could enhance nutritional status, improve diet quality, and raise awareness about healthy and balanced nutrition for individuals with MS.
本研究旨在评估被诊断为多发性硬化症（MS）的女性的一些血清参数、饮食炎症指数（DII）、生活质量、抑郁状况和营养状况之间的关系。共有153名年龄在20至50岁之间、居住在安卡拉的女性参与了该研究，其中包括73名MS患者和80名对照组女性。该研究评估了一般特征、人体测量指标、多发性硬化症生活质量量表（MSQOL - 54）、贝克抑郁量表 - 21（BDI）、地中海饮食评分（MIND）、3天食物消费记录、健康饮食指数 - 2015（HEI - 2015）、DII以及生化检查结果。MS组的平均腰围（84.5 ± 12.22厘米）显著高于对照组（80.5 ± 10.60厘米）（P < 0.05）。MS组的平均BDI评分为12.9 ± 9.66分，对照组为7.9 ± 6.16分，MS组得分显著更高（P < 0.05）。MS组的平均MIND饮食评分（6.3 ± 1.90）显著低于对照组（6.9 ± 1.71）（P < 0.05）。对照组的平均DII和HEI - 2015评分（分别为2.2 ± 2.34和44.6 ± 9.86）低于MS组（2.4 ± 2.43和44.8 ± 12.69）。在MS组中，64.2%的人饮食不佳，而对照组中这一比例为72.5%。与MS组的34.6%相比，对照组中有27.5%的人饮食需要改善。本研究提供了关于MS患者人体测量指标、血清参数、抑郁状况，尤其是营养状况的详细见解。鉴于MS患者的MIND饮食评分显著较低，实施个体化医学营养治疗将是有益的。这种方法可以改善营养状况、提高饮食质量，并提高MS患者对健康均衡营养的认识。
