Murase T, Takashi M, Aota Y, Shimoji T, Miyake K, Mitsuya H
Hinyokika Kiyo. 1985 Aug;31(8):1459-62.
Workers in the dye manufacturing industry have a high risk of urinary bladder cancer. There may also be a high relative risk of bladder cancer in occupational dye users. Nine occupational dye users were found to have bladder cancer. The period of engaging with dye work ranged from 5 to 40 years. Seven patients had bladder cancer and the other 2 patients had lesions both in the bladder and in the renal pelvis. Histopathology of all cases was transitional cell carcinoma. Three cases were classified into grade 1 and 6 cases into grade 2. One patient died of bladder cancer. The other 8 patients are alive. Four cases recurred after TUR therapy. It is necessary to establish systemic mass screening examination of occupational dye users for the early diagnosis of bladder cancer.
染料制造业的工人患膀胱癌的风险很高。职业性染料使用者患膀胱癌的相对风险也可能很高。发现9名职业性染料使用者患有膀胱癌。从事染料工作的时间为5至40年。7例患者患有膀胱癌，另外2例患者膀胱和肾盂均有病变。所有病例的组织病理学均为移行细胞癌。3例为1级，6例为2级。1例患者死于膀胱癌。其他8例患者存活。4例经TUR治疗后复发。有必要对职业性染料使用者进行系统性大规模筛查，以便早期诊断膀胱癌。
