Geddes A M, Clarke P D
J Antimicrob Chemother. 1977 Jul;3 Suppl B:101-2. doi: 10.1093/jac/3.suppl_b.101.
In vitro studies carried out in this Department confirmed the high activity of mecillinam against Salmonella spp. As a result we set up a study to investigate the efficacy of mecillinam in patients suffering from enteric fever. To date 13 out of 15 patients with typhoid or paratyphoid fever have been successfully treated with this new amidinopenicillanic acid antibiotic.
本部门进行的体外研究证实了美西林对沙门氏菌属具有高活性。因此,我们开展了一项研究,以调查美西林对伤寒患者的疗效。迄今为止,15例伤寒或副伤寒热患者中有13例已成功接受这种新型脒基青霉烷酸抗生素治疗。