Uda Kenji, Awaya Takayuki, Fukuoka Toshiki, Iwakoshi Tomotaka, Nagamatsu Hinako, Ishii Kazuki, Abe Takashi, Suzuki Osamu, Nagashima Yoshitaka, Tanei Takafumi, Nishimura Yusuke, Saito Ryuta
Department of Neurosurgery and Spine Centre, Nagoya Ekisaikai Hospital, Nagoya, Japan.
Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Global Spine J. 2025 Aug 20:21925682251370280. doi: 10.1177/21925682251370280.
Study DesignRetrospective observational study.ObjectivesTo evaluate 1-year clinical outcomes of vertebral body stenting (VBS) for osteoporotic vertebral fractures (OVFs) and compare its effectiveness in patients with and without poor prognostic magnetic resonance imaging (MRI) findings.MethodsEighty-seven patients (mean age, 79.2 years) who underwent VBS for OVF were analyzed. Those with severe vertebral body injury requiring additional posterior fixation or unsuccessful stent deployment were excluded. Outcomes included changes in pain (Numerical Rating Scale [NRS]), perioperative complications, adjacent vertebral fractures (AVF), and development of non-union or delayed vertebral collapse. Radiographic parameters-anterior vertebral height (AVH), middle vertebral height (MVH), posterior vertebral height (PVH), and vertebral angle (VA)-were assessed preoperatively, on postoperative day 1 (POD1), postoperative month 6 (POM6), and POM12. Patients were stratified based on the presence of poor prognostic MRI findings, defined as high or diffuse low-intensity signals on T2-weighted MRI.ResultsNRS significantly improved from 6.2 to 2.8 postoperatively. Cement leakage occurred without symptoms in 16% of patients. Non-union was not observed, and delayed vertebral collapse occurred without symptoms in three patients. Radiographic improvements in AVH, MVH, PVH, and VA were significant at POD1 and largely maintained at POM12. Patients with poor prognostic MRI findings showed significantly greater improvements in AVH, MVH, and VA at POD1 and POM12.ConclusionsVBS effectively maintained vertebral height and prevented non-union and delayed collapse at 1 year postoperatively. Favorable outcomes were also seen in patients with poor prognostic MRI findings, supporting the utility of MRI as a treatment selection criterion.
研究设计
回顾性观察性研究。
目的
评估椎体支架植入术(VBS)治疗骨质疏松性椎体骨折(OVF)的1年临床疗效,并比较其在有和没有不良预后磁共振成像(MRI)表现的患者中的有效性。
方法
分析87例接受VBS治疗OVF的患者(平均年龄79.2岁)。排除那些椎体损伤严重需要额外后路固定或支架植入失败的患者。观察指标包括疼痛变化(数字评分量表[NRS])、围手术期并发症、相邻椎体骨折(AVF)以及骨不连或延迟椎体塌陷的发生情况。术前、术后第1天(POD1)、术后6个月(POM6)和术后12个月(POM12)评估影像学参数——椎体前缘高度(AVH)、椎体中部高度(MVH)、椎体后缘高度(PVH)和椎体角度(VA)。根据不良预后MRI表现的有无对患者进行分层,不良预后MRI表现定义为T2加权MRI上的高信号或弥漫性低信号。
结果
术后NRS评分从6.2显著改善至2.8。16%的患者发生了无症状的骨水泥渗漏。未观察到骨不连,3例患者发生了无症状的延迟椎体塌陷。AVH、MVH、PVH和VA在POD1时影像学改善显著,且在POM12时基本维持。有不良预后MRI表现的患者在POD1和POM12时AVH、MVH和VA的改善更为显著。
结论
VBS在术后1年有效维持了椎体高度,预防了骨不连和延迟塌陷。有不良预后MRI表现的患者也取得了良好的疗效,支持将MRI作为治疗选择标准的实用性。