Nasir Hijrah, Duclos Martine, Bagheri Reza, Cole Alistair, Baker Julien S, Thivel David, Dutheil Frederic
Université Clermont Auvergne, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), CNRS, LaPSCo, Clermont-Ferrand, France.
Department of Sport Medicine and Functional Exploration, Université Clermont Auvergne, INRAE, UNH, CHU Clermont-Ferrand, Clermont-Ferrand, France.
PLoS One. 2025 Aug 20;20(8):e0328678. doi: 10.1371/journal.pone.0328678. eCollection 2025.
Despite numerous meta-analyses on the effects of leisure time sedentary behavior, the effect of sedentary behavior at work on mental health is largely under debate. We aimed to systematically identify and synthetize the literature examining the association between sedentary behavior at work on mental health.
PubMed, Embase, Cochrane, and Psycinfo databases were searched for articles reporting risks for mental health due to occupational sedentary behavior. We computed random-effects meta-analysis using all risks and both intermediate and severe levels of mental health issues, following by sensitivity analysis on severe mental health issues using 1) all risks, then only 2) fully adjusted and 3) crude or less adjusted lowest risks (pessimistic models), and 4) fully adjusted and 5) crude or less adjusted highest risks (optimistic models). We conducted meta-regression on possible influencing factors.
We included 12 studies in the systematic review and 7 in the meta-analysis, for a total of 40,314 workers (35 years old, 65.5% men). Exposure to sedentary behavior at work increased the risk of intermediate and severe mental health issues by +34% (95 CI 18-49%). All sensitivity analyses on severe mental health issues were also significant, whatever the model: + 35% (12-58%) using all risks, 39% (15-63%) using fully adjusted pessimistic model, + 36% (13-59%) using crude or less adjusted pessimistic model, 85% (27-143%) using fully adjusted optimistic model, + 85% (26-143%) using crude or less adjusted optimistic model. Age may have an increased risk of mental health issue when exposed to occupational sedentary behavior, while high education reduced the risk.
Our meta-analysis shows that occupational sedentary behavior increases the risk of mental health issue. Inconsistent results precluded robust conclusion for variables that may further influence this risk.
尽管针对休闲时间久坐行为的影响进行了大量的荟萃分析,但工作中的久坐行为对心理健康的影响仍存在很大争议。我们旨在系统地识别和综合研究工作中的久坐行为与心理健康之间关联的文献。
在PubMed、Embase、Cochrane和Psycinfo数据库中检索报告职业久坐行为导致心理健康风险的文章。我们使用所有风险以及心理健康问题的中度和重度水平进行随机效应荟萃分析,随后对重度心理健康问题进行敏感性分析,分析内容包括:1)所有风险,2)仅完全调整后的风险,3)粗略或调整较少的最低风险(悲观模型),4)完全调整后的风险,5)粗略或调整较少的最高风险(乐观模型)。我们对可能的影响因素进行了荟萃回归分析。
我们在系统评价中纳入了12项研究,在荟萃分析中纳入了7项研究,共计40314名工人(年龄35岁,65.5%为男性)。工作中久坐行为会使中度和重度心理健康问题的风险增加34%(95%置信区间18 - 49%)。对重度心理健康问题的所有敏感性分析也均具有显著性,无论采用何种模型:使用所有风险时为35%(12 - 58%),使用完全调整后的悲观模型时为39%(15 - 63%),使用粗略或调整较少的悲观模型时为36%(13 - 59%),使用完全调整后的乐观模型时为85%(27 - 143%),使用粗略或调整较少的乐观模型时为85%(26 - 143%)。暴露于职业久坐行为时,年龄可能会增加心理健康问题的风险,而高学历则会降低风险。
我们的荟萃分析表明,职业久坐行为会增加心理健康问题的风险。结果的不一致性使得无法就可能进一步影响该风险的变量得出确凿结论。