• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Through a Translational Lens: How Does Inflammation Contribute to the Pathogenesis of Asthma and Allergy?透过转化医学视角：炎症如何促使哮喘与过敏的发病机制？
J Inflamm Res. 2025 Aug 15;18:11189-11190. doi: 10.2147/JIR.S532374. eCollection 2025.
2
The Lived Experience of Autistic Adults in Employment: A Systematic Search and Synthesis.成年自闭症患者的就业生活经历：系统检索与综述
Autism Adulthood. 2024 Dec 2;6(4):495-509. doi: 10.1089/aut.2022.0114. eCollection 2024 Dec.
3
Short-Term Memory Impairment短期记忆障碍
4
[Guidelines for the prevention and management of bronchial asthma (2024 edition)].[支气管哮喘防治指南（2024年版）]
Zhonghua Jie He He Hu Xi Za Zhi. 2025 Mar 12;48(3):208-248. doi: 10.3760/cma.j.cn112147-20241013-00601.
5
Fabricating mice and dementia: opening up relations in multi-species research制造小鼠与痴呆症：开启多物种研究中的关联
6
The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
Psychopharmacol Bull. 2024 Jul 8;54(3):8-59.
7
Prescription of Controlled Substances: Benefits and Risks管制药品的处方：益处与风险
8
Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches?哮喘的病理生理学：我们目前的理解对新的治疗方法有什么启示？
J Allergy Clin Immunol. 2011 Sep;128(3):495-505. doi: 10.1016/j.jaci.2011.06.052. Epub 2011 Jul 31.
9
The role of mast cells in allergic rhinitis.肥大细胞在变应性鼻炎中的作用。
PeerJ. 2025 Jul 30;13:e19734. doi: 10.7717/peerj.19734. eCollection 2025.
10
A tutorial on discourse analysis in healthy and pathological ageing.健康和病态老化中的话语分析教程。
Int J Lang Commun Disord. 2024 Jan-Feb;59(1):94-109. doi: 10.1111/1460-6984.12919. Epub 2023 Jun 22.

本文引用的文献

1
A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma.气道壁的单细胞空间图谱揭示了健康和哮喘状态下的促炎细胞生态系统及其相互作用。
Nat Immunol. 2025 May 21. doi: 10.1038/s41590-025-02161-3.
2
Engineering human immune organoids for translational immunology.用于转化免疫学的工程化人类免疫类器官
Bioact Mater. 2024 Oct 18;44:164-183. doi: 10.1016/j.bioactmat.2024.10.010. eCollection 2025 Feb.
3
Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics.利用单细胞和空间转录组学分析细胞身份和组织结构。
Nat Rev Mol Cell Biol. 2025 Jan;26(1):11-31. doi: 10.1038/s41580-024-00768-2. Epub 2024 Aug 21.
4
T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling.T 细胞与气道平滑肌相互作用：哮喘气道炎症和重塑的关键驱动因素。
Am J Physiol Lung Cell Mol Physiol. 2024 Sep 1;327(3):L382-L394. doi: 10.1152/ajplung.00121.2024. Epub 2024 Jul 16.
5
Gene editing in allergic diseases: Identification of novel pathways and impact of deleting allergen genes.基因编辑在过敏性疾病中的应用：新型通路的鉴定和过敏原基因缺失的影响。
J Allergy Clin Immunol. 2024 Jul;154(1):51-58. doi: 10.1016/j.jaci.2024.03.016. Epub 2024 Mar 29.
6
Systems Immunology: Origins.系统免疫学：起源
J Immunol. 2023 Apr 1;210(7):845-847. doi: 10.4049/jimmunol.2200631.
7
Crosstalk between CD4 T Cells and Airway Smooth Muscle in Pediatric Obesity-related Asthma.小儿肥胖相关哮喘中CD4 T细胞与气道平滑肌之间的相互作用
Am J Respir Crit Care Med. 2023 Feb 15;207(4):461-474. doi: 10.1164/rccm.202205-0985OC.
8
Nanotubes connect CD4+ T cells to airway smooth muscle cells: novel mechanism of T cell survival.纳米管将CD4+ T细胞与气道平滑肌细胞相连：T细胞存活的新机制。
J Immunol. 2015 Jun 15;194(12):5626-34. doi: 10.4049/jimmunol.1401718. Epub 2015 May 1.
9
T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis.T淋巴细胞通过整合素和CD44黏附于气道平滑肌细胞，并诱导平滑肌细胞DNA合成。
J Exp Med. 1994 Sep 1;180(3):807-16. doi: 10.1084/jem.180.3.807.

透过转化医学视角：炎症如何促使哮喘与过敏的发病机制？

Through a Translational Lens: How Does Inflammation Contribute to the Pathogenesis of Asthma and Allergy?

作者信息

Koziol-White Cynthia J, Panettieri Reynold A

机构信息

Rutgers Institute of Translational Medicine and Science, Rutgers University, New Brunswick, NJ, USA.

出版信息

J Inflamm Res. 2025 Aug 15;18:11189-11190. doi: 10.2147/JIR.S532374. eCollection 2025.

DOI:10.2147/JIR.S532374
PMID:40837003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12363547/
Abstract

Single cell and animal models have been critical to understanding how inflammation that occurs in asthma and allergy contributes to the pathogenesis of these allergic diseases. Recent technological advances enabled scientific discoveries to be translated into clinically relevant approaches.

摘要

单细胞模型和动物模型对于理解哮喘和过敏中发生的炎症如何导致这些过敏性疾病的发病机制至关重要。最近的技术进步使科学发现能够转化为临床相关方法。