Xue Lili, Jiang Yaqiong, Guo Yongli, Ma Hongyan, Jiang Lingling, Wang Xiaoyu, Kang Xinyi, Wang Ying, Cao Jiachen, Chen Liping
Affiliated Hospital 2 of Nantong University, Department of Obstetrics and Gynecology, Nantong First People's Hospital, Nantong, Jiangsu, China.
J Med Biochem. 2025 Jul 4;44(4):831-839. doi: 10.5937/jomb0-56599.
This study aims to evaluate the effectiveness of manual lymphatic drainage (MLD) combined with abdominal breathing in rehabilitating postpartum perineal oedema and Serum IL-6, IL-10, TNF-a.
A total of 172 primiparous women who delivered in our hospital between January 2022 and June 2023 were randomly assigned to either the observation group (n=86) or the control group (n=86). The control group received routine midwifery care, while the observation group received additional MLD and abdominal breathing training. Outcomes measured included pain levels, induration diameter, comfort, emotional state, recovery time, and clinical efficacy. Inflammatory markers, including C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), interleukin-6 (IL-6), interleukin-10 (IL-10), and tumour necrosis factor-alpha (TNF-a), were also assessed.
Both groups demonstrated significant reductions in Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores after treatment (P<0.05), with the observation group showing a greater decrease (P<0.05). The observation group exhibited a significantly shorter recovery time (3.6±1.8 days vs. 4.2±2.5 days, P<0.05) and reported higher comfort levels and lower pain scores than the control group (P<0.05). The effective treatment rate was 97.68% in the observation group, significantly higher than the 82.56% observed in the control group (P<0.05). Inflammatory markers, including IL-6 and TNF-a, showed a significant reduction in the observation group.
Combining MLD and abdominal breathing reduces postpartum perineal oedema effectively, alleviates pain, and enhances recovery. It also lowers inflammatory markers (IL-6, TNF-a) and increases IL-10, promoting faster healing and improved maternal comfort.
本研究旨在评估手法淋巴引流（MLD）联合腹式呼吸对产后会阴水肿及血清白细胞介素-6（IL-6）、白细胞介素-10（IL-10）、肿瘤坏死因子-α（TNF-α）恢复的有效性。
选取2022年1月至2023年6月在我院分娩的172例初产妇，随机分为观察组（n=86）和对照组（n=86）。对照组接受常规助产护理，观察组在此基础上接受额外的MLD和腹式呼吸训练。测量的结果包括疼痛程度、硬结直径、舒适度、情绪状态、恢复时间和临床疗效。还评估了炎症标志物，包括C反应蛋白（CRP）、红细胞沉降率（ESR）、白细胞介素-6（IL-6）、白细胞介素-10（IL-10）和肿瘤坏死因子-α（TNF-α）。
两组治疗后焦虑自评量表（SAS）和抑郁自评量表（SDS）评分均显著降低（P<0.05），观察组下降幅度更大（P<0.05）。观察组恢复时间显著短于对照组（3.6±1.8天 vs. 4.2±2.5天，P<0.05），舒适度更高，疼痛评分更低（P<0.05）。观察组有效治疗率为97.68%，显著高于对照组的82.56%（P<0.05）。观察组炎症标志物IL-6和TNF-α显著降低。
MLD与腹式呼吸相结合可有效减轻产后会阴水肿，缓解疼痛，促进恢复。还可降低炎症标志物（IL-6、TNF-α）水平，升高IL-10水平，促进愈合加快，提高产妇舒适度。
