Department of Sports Rehabilitation, School of Physical Education, Anqing Normal University, Anhui, China.
School of Physical Education of Chaohu University, Anhui, China.
Trials. 2024 May 30;25(1):351. doi: 10.1186/s13063-024-08193-8.
Patients with chronic obstructive pulmonary disease (COPD) often suffer from a combination of mild cognitive impairment (MCI) and a significant reduction in their quality of life. In the exercise programme of pulmonary rehabilitation (PR), pulmonary rehabilitation intervention is often carried out by enhancing respiratory function. Strong abdominal breathing is a kind of breathing method, through which the diaphragm can be exercised, thereby enhancing the deflection distance of the diaphragm during breathing and improving respiratory function. The inversion trainer can meet the different angles of head-down training and also has the characteristics of low cost, easy to operate, and use a wide range of scenarios. According to currently available data, strong abdominal breathing in combination with head-down position has not yet been used in pulmonary rehabilitation in this type of rehabilitation programme. It is valuable to use this device to study PR of cognitive function in patients with COPD.
This study was a 12-week single-centre randomised controlled trial and blinding the assessors and data processors of the test. Recruitment is planned for January 1, 2024. It is expected that 81 patients with stable COPD combined with MCI will be recruited and randomly assigned to the head-down strong abdominal breathing group (HG), the fitness qigong eight-duanjin group (BDJ), and the control group (CG) in a 1:1:1 ratio. Using fNIRS (functional near-infrared spectroscopy) to assess brain oxygen availability before and after pulmonary rehabilitation in three periods: before, during and after the intervention. Cognitive functioning is also assessed using the Overall Cognitive Assessment Scale, the Specific Cognitive Functioning Assessment Scale and the Cognitive Behavioural Ability Test.
The Specialised Committee on Scientific Research and Academic Ethics of the Academic Committee of Anqing Normal University approved the project (ANU2023001). China Clinical Trial Registry approved the study (ChiCTR2300075400) with a registration date of 2023/09/04.
The aim of this study was to explore novel exercise rehabilitation methods to improve cognitive function in COPD patients. It results in a lower financial burden and higher participation in pulmonary rehabilitation and improves the quality of survival of patients with COPD.
慢性阻塞性肺疾病（COPD）患者常同时患有轻度认知障碍（MCI）和生活质量显著下降。在肺康复（PR）的运动方案中，肺康复干预通常通过增强呼吸功能来进行。强力腹式呼吸是一种呼吸方式，通过这种呼吸方式可以锻炼膈肌，从而增加呼吸时膈肌的偏距，改善呼吸功能。倒立训练器可以满足头低位训练的不同角度，具有成本低、操作简单、使用场景广泛的特点。根据目前的数据，在这种康复方案的肺康复中，还没有将强力腹式呼吸与头低位结合使用。使用该设备研究 COPD 患者认知功能的 PR 具有重要价值。
这是一项为期 12 周的单中心随机对照试验，评估者和数据处理者均设盲。计划于 2024 年 1 月 1 日开始招募患者。预计将招募 81 例稳定期 COPD 合并 MCI 患者，按 1:1:1 的比例随机分为头低位强力腹式呼吸组（HG）、健身气功八段锦组（BDJ）和对照组（CG）。使用功能近红外光谱（fNIRS）在三个时期（干预前、干预中和干预后）评估肺康复前后大脑氧合的可用性。认知功能也使用整体认知评估量表、特定认知功能评估量表和认知行为能力测试进行评估。
安庆师范大学学术委员会科学研究与学术伦理专门委员会批准了该项目（ANU2023001）。中国临床试验注册中心批准了该研究（ChiCTR2300075400），注册日期为 2023 年 9 月 4 日。
本研究旨在探索新的运动康复方法，以改善 COPD 患者的认知功能。这会降低财务负担，提高 COPD 患者对肺康复的参与度，提高患者的生存质量。
