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Prophylactic surgical left atrial appendage occlusion: More questions than answers!

作者信息

Xu Jianguo, Whitlock Richard P, Belley-Cote Emilie P

机构信息

Population Health Research Institute, Hamilton, Canada.

Department of Surgery, McMaster University, Hamilton, Canada.

出版信息

Am Heart J Plus. 2025 Aug 9;58:100589. doi: 10.1016/j.ahjo.2025.100589. eCollection 2025 Oct.

DOI:10.1016/j.ahjo.2025.100589
PMID:40837622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12361803/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beec/12361803/9e568305b24a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beec/12361803/9e568305b24a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beec/12361803/9e568305b24a/gr1.jpg

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本文引用的文献

1
The clinical impact of prophylactic concomitant left atrial appendage occlusion during cardiac surgery: A systematic review and meta-analysis.心脏手术期间预防性同期左心耳封堵的临床影响:一项系统评价和荟萃分析。
Am Heart J Plus. 2025 Mar 26;53:100534. doi: 10.1016/j.ahjo.2025.100534. eCollection 2025 May.
2
The left atrial appendage exclusion for prophylactic stroke reduction (LEAAPS) trial: Rationale and design.左心耳封堵预防卒中减少(LEAAPS)试验:原理与设计
Am Heart J. 2025 Jun;284:94-102. doi: 10.1016/j.ahj.2024.10.006. Epub 2024 Oct 11.
3
Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.
心脏手术中的左心耳封堵术预防中风。
N Engl J Med. 2021 Jun 3;384(22):2081-2091. doi: 10.1056/NEJMoa2101897. Epub 2021 May 15.
4
GRADE guidelines: 4. Rating the quality of evidence--study limitations (risk of bias).GRADE 指南:4. 评估证据质量——研究局限性(偏倚风险)。
J Clin Epidemiol. 2011 Apr;64(4):407-15. doi: 10.1016/j.jclinepi.2010.07.017. Epub 2011 Jan 19.
5
Comparison of evidence of treatment effects in randomized and nonrandomized studies.随机对照研究与非随机对照研究中治疗效果证据的比较。
JAMA. 2001 Aug 15;286(7):821-30. doi: 10.1001/jama.286.7.821.