Qu Jiang-Lei, Lu Hai-Yang, Fu Xiao-Bo, Gai Wen-Tao
Department of Urology Surgery, Qingdao Hiser Hospital Affiliated of Qingdao University (Qingdao Traditional Chinese Medicine Hospital), Qingdao 266033, Shandong Province, China.
Department of Oncology, Qingdao Hiser Hospital North Branch Affiliated of Qingdao University (Hongdao People's Hospital of Qingdao), Qingdao 266033, Shandong Province, China.
World J Psychiatry. 2025 Aug 19;15(8):102835. doi: 10.5498/wjp.v15.i8.102835.
The development of prostate cancer (PC) frequently intensifies negative emotional states, such as anxiety and depression, which compromise the effectiveness of radical surgery and reduce treatment adherence. In this study, we hypothesized that psychological resilience plays a crucial role in this process and explored its impact.
To investigate the association of resilience with anxiety and depression in patients with PC and to analyze the influencing factors.
We selected 147 patients with PC who visited Qingdao Traditional Chinese Medicine Hospital from January 2022 to June 2024. The resilience scores of patients with PC were assessed using the Connor-Davidson Resilience Scale (CD-RISC) from the tenacity, self-improvement, and optimism dimensions. Based on the total CD-RISC score, patients were categorized into groups A (total CD-RISC score > 63 points, = 69) and B (total CD-RISC score ≤ 63 points, = 78) for comparative analysis of anxiety [Hamilton Anxiety Rating Scale (HAMA)], depression [Hamilton Depression Rating Scale (HAMD)], sexual function [International Index of Erectile Function-5 (IIEF-5) and Sexual Life Quality Questionnaire-Quality of Life (SLQQ-QOL)], and quality of life [the EORTC Core Quality of Life Questionnaire (QLQ-C30)]. The association between CD-RISC and the above indicators was analyzed with Spearman correlation coefficients, and the influencing factors of resilience in patients with PC were identified with binary logistic regression.
Group A demonstrated statistically lower HAMA and HAMD scores and markedly higher scores of IIEF-5, SLQQ-QOL, and various QLQ-C30 aspects. Correlation analysis revealed that CD-RISC was significantly negatively correlated with HAMA and HAMD scores and significantly positively correlated with IIEF-5, SLQQ-QOL, and QLQ-C30 total scores. Binary logistic regression analysis revealed educational and per capita monthly household income levels as significant influencing factors of resilience in patients with PC.
Our results indicate a significant correlation of resilience with anxiety and depression in patients with PC. The milder the anxiety and depression emotions in patients, the higher their resilience. Further, assisting patients with PC to improve their educational and per capita monthly household income levels will help their resilience to some extent.
前列腺癌（PC）的发展常常会加剧焦虑和抑郁等负面情绪状态，这会损害根治性手术的效果并降低治疗依从性。在本研究中，我们假设心理韧性在这一过程中起关键作用，并探讨了其影响。
调查PC患者的心理韧性与焦虑和抑郁之间的关联，并分析影响因素。
我们选取了2022年1月至2024年6月期间到青岛市中医医院就诊的147例PC患者。使用Connor-Davidson心理韧性量表（CD-RISC）从坚韧、自我提升和乐观维度评估PC患者的心理韧性得分。根据CD-RISC总分，将患者分为A组（CD-RISC总分>63分，n = 69）和B组（CD-RISC总分≤63分，n = 78），以比较分析焦虑[汉密尔顿焦虑量表（HAMA）]、抑郁[汉密尔顿抑郁量表（HAMD）]、性功能[国际勃起功能指数-5（IIEF-5）和性生活质量问卷-生活质量（SLQQ-QOL）]以及生活质量[欧洲癌症研究与治疗组织核心生活质量问卷（QLQ-C30）]。用Spearman相关系数分析CD-RISC与上述指标之间的关联，并用二元逻辑回归确定PC患者心理韧性的影响因素。
A组的HAMA和HAMD得分在统计学上较低，而IIEF-5、SLQQ-QOL以及QLQ-C30各方面的得分明显较高。相关性分析显示，CD-RISC与HAMA和HAMD得分显著负相关，与IIEF-5、SLQQ-QOL和QLQ-C30总分显著正相关。二元逻辑回归分析显示，教育程度和家庭月人均收入水平是PC患者心理韧性的重要影响因素。
我们的结果表明，PC患者的心理韧性与焦虑和抑郁之间存在显著相关性。患者的焦虑和抑郁情绪越轻，其心理韧性越高。此外，帮助PC患者提高教育程度和家庭月人均收入水平在一定程度上有助于增强他们的心理韧性。
