Lee S T
Ann Acad Med Singap. 1985 Oct;14(4):595-603.
This is a report of 12 cases of congenital median cleft deformity of the upper lip seen in the Department of Plastic Surgery, Singapore General Hospital. This deformity is extremely rare and there are probably not more than 100 cases reported in the literature. The classification, nomenclature, pathogenesis and embryological development of median clefts are still not clearly understood. An analysis of the 12 cases is made with the view to clarify the nomenclature and classification of median clefts. An attempt is also made to explain the embryogenesis of this deformity and its common association with cranial and other facial defects.
这是一篇关于新加坡中央医院整形外科收治的12例先天性上唇正中裂畸形病例的报告。这种畸形极为罕见,文献报道可能不超过100例。正中裂的分类、命名、发病机制及胚胎发育仍未完全明确。本文对这12例病例进行分析,旨在明确正中裂的命名和分类。同时,尝试解释这种畸形的胚胎发生过程及其与颅骨和其他面部缺陷的常见关联。