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肯尼亚内罗毕一家医院在三年时间里对唇腭裂病例的处理模式。

Pattern of clefts of the lip and palate managed over a three year period at a Nairobi hospital in Kenya.

作者信息

Onyango J F, Noah S

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, University of Nairobi, P.O. Box 19676, Nairobi, Kenya.

出版信息

East Afr Med J. 2005 Dec;82(12):649-51. doi: 10.4314/eamj.v82i12.9371.

Abstract

BACKGROUND

The pattern of cleft lip and palate in the African population remains uncertain. The few studies of clefts in African populations have suggested that the pattern of these defects may be significantly different from those reported in other population groups. However, most of these studies have been based on very small sample sizes bringing into question the validity of those findings.

OBJECTIVE

To analyse the pattern of cleft lip and palate cases managed at a Nairobi hospital.

DESIGN

A retrospective descriptive study.

SETTING

Gertrude's Garden Children's Hospital, a private exclusive children's hospital in Nairobi, where cleft lip and palate treatment was being offered at subsidised rates to needy children under the sponsorship of an international organization.

SUBJECTS

Three hundred and nine cases were seen during the study period.

RESULTS

Age at presentation ranged between 1 week and 45 years, with 75% presenting between 0-5 years. The average age was 10 months. Gestation histories were missing for most cases but for those with gestation histories none were significant. Most children ranked between first to third birth orders, suggesting birth to young mothers. Six cases of associated deformities were identified among the cases. No syndromic clefts were seen. The most common cleft deformity was the cleft lip and palate (CL+P) followed by isolated cleft lip (CL). Isolated cleft palate was least common. There was a male preponderance in all cleft types and most of the clefts occurred on the left side.

CONCLUSION

The pattern of clefts in this study does not differ significantly from those reported in the literature for the non-African populations.

摘要

背景

非洲人群中唇腭裂的模式仍不明确。少数关于非洲人群腭裂的研究表明,这些缺陷的模式可能与其他人群组报告的模式有显著差异。然而,这些研究大多基于非常小的样本量,这使得这些发现的有效性受到质疑。

目的

分析在内罗毕一家医院接受治疗的唇腭裂病例模式。

设计

一项回顾性描述性研究。

地点

格特鲁德花园儿童医院,内罗毕一家私立专科医院,在一个国际组织的赞助下,以补贴价格为贫困儿童提供唇腭裂治疗。

对象

研究期间共诊治309例病例。

结果

就诊年龄在1周至45岁之间,75%的患者在0至5岁之间就诊。平均年龄为10个月。大多数病例没有妊娠史,但有妊娠史的病例均无异常。大多数儿童的出生顺序在第一至第三之间,表明母亲较为年轻。在这些病例中发现了6例合并畸形。未发现综合征性腭裂。最常见的腭裂畸形是唇腭裂(CL+P),其次是单纯性唇裂(CL)。单纯性腭裂最不常见。所有腭裂类型中男性居多,且大多数腭裂发生在左侧。

结论

本研究中腭裂的模式与文献中报道的非非洲人群的模式没有显著差异。

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