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运用统计建模确定耐甲氧西林感染的趋势

Trend determination of methicillin-resistant infections with statistical modeling.

作者信息

Hurdoganoglu Ulas, Gokbulut Nezihal, Guler Emrah, Suer Kaya, Hincal Evren

机构信息

Department of Molecular Biology and Genetics, Near East University Faculty of Arts and Sciences, Nicosia, TRNC.

Department of Mathematics, Near East University Faculty of Arts and Sciences, Nicosia, TRNC.

出版信息

North Clin Istanb. 2025 Feb 3;12(1):12-20. doi: 10.14744/nci.2023.66891. eCollection 2025.

Abstract

OBJECTIVE

The purpose of this study is to analyze the situation of Methicillin-Resistant (MRSA) in TRNC by examining the prevalence of Community-acquired Methicillin-Resistant (CA-MRSA)/Hospital-acquired Methicillin-Resistant (HA-MRSA) cases, the acceleration of CA-MRSA/HA-MRSA patients from past to present, the impact of pandemic, gender and age on MRSA cases.

METHODS

In order to analyze the trend of MRSA cases and the effects of selected parameters on MRSA cases, statistical tests are employed to the obtained data including ANOVA test, regression analysis tests and Post-hoc Tukey test.

RESULTS

Incidence rate of MRSA carriage in the community has increased over the years to 45.6%. p-value of the relationship between community-acquired MRSA cases and hospital-acquired MRSA cases is less than 0.05. The results also revealed that the p-value of both the relationship between COVID-19 and MRSA cases and the relationship between 50+ age and MRSA cases are significant. On the other hand, p-value of the relationship between gender and MRSA cases is found to be greater than 0.05.

CONCLUSION

It is concluded that MRSA carriage in the community has increased over the years and CA-MRSA and HA-MRSA cases are related since p<0.05. Moreover, it's revealed that there is an effect of COVID-19 pandemic and 50+ age (66% of the cases) on MRSA cases because of p<0.05 while the gender is not an effect for MRSA cases in the country, since p-value for gender comparison is greater than 0.05.

摘要

目的

本研究旨在通过检查社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)/医院获得性耐甲氧西林金黄色葡萄球菌(HA-MRSA)病例的流行情况、CA-MRSA/HA-MRSA患者从过去到现在的增长情况、大流行、性别和年龄对耐甲氧西林金黄色葡萄球菌(MRSA)病例的影响,来分析北塞浦路斯土耳其共和国的MRSA情况。

方法

为了分析MRSA病例的趋势以及所选参数对MRSA病例的影响,对获得的数据采用统计检验,包括方差分析检验、回归分析检验和事后Tukey检验。

结果

多年来社区中MRSA携带的发病率已上升至45.6%。社区获得性MRSA病例与医院获得性MRSA病例之间关系的p值小于0.05。结果还显示,COVID-19与MRSA病例之间的关系以及50岁以上年龄与MRSA病例之间的关系的p值均具有显著性。另一方面,发现性别与MRSA病例之间关系的p值大于0.05。

结论

得出的结论是,多年来社区中MRSA携带率有所上升,且由于p<0.05,CA-MRSA和HA-MRSA病例相关。此外,由于p<0.05,表明COVID-19大流行和50岁以上年龄(占病例的66%)对MRSA病例有影响,而在该国性别对MRSA病例没有影响,因为性别比较的p值大于0.05。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02a1/12364480/d1c8f3e46bb2/NCI-12-012-g001.jpg

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