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葡萄膜炎患者青光眼/眼压升高的患病率及预后

Prevalence and Prognosis of Glaucoma/Elevated Intraocular Pressure in Patients with Uveitis.

作者信息

Esen Barış Mine, Ateş Halil, Güven Yılmaz Suzan

机构信息

Ege University Faculty of Medicine, Department of Ophthalmology, İzmir, Türkiye.

出版信息

Turk J Ophthalmol. 2025 Aug 21;55(4):215-220. doi: 10.4274/tjo.galenos.2025.53498.

DOI:10.4274/tjo.galenos.2025.53498
PMID:40838536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12372549/
Abstract

OBJECTIVES

To evaluate the prevalence and clinical course of elevated intraocular pressure (EIP) and glaucoma in different types of uveitis.

MATERIALS AND METHODS

A retrospective chart review was performed for patients who were treated for any kind of uveitis at Ege University Ophthalmology Department between January 2003 and January 2023. Patients with transient/persistent increase in intraocular pressure (IOP), who were already under treatment with antiglaucoma medications at the initial examination, or who were diagnosed with glaucoma during follow-up were included. Demographic features, uveitis type, time between uveitis and glaucoma/EIP diagnoses, topical and systemic treatments for uveitis, and antiglaucoma medications and surgeries were recorded.

RESULTS

A total of 2176 patient files (1206 anterior uveitis [AU], 247 intermediate uveitis [IU], 165 posterior uveitis [PU], 558 panuveitis [PanU]) were reviewed and 594 eyes of 440 (20.2%) patients (205 female, 235 male) were included in the study (292 eyes with AU, 80 eyes with IU, 44 eyes with PU, and 178 eyes with PanU). Glaucoma was observed in 220 eyes (37.0%) and EIP in 374 eyes (63.0%). Glaucoma was present in 120 eyes with AU, 23 eyes with IU, 13 eyes with PU, and 64 eyes with PanU. IOP was controlled with medical treatment in 458 eyes (77.1%) while glaucoma surgery/laser was needed in 113 eyes (19.0%). No treatment was required for 23 eyes (3.9%).

CONCLUSION

The prevalence rate of glaucoma/EIP was 20.3%. Glaucoma was most observed in eyes with AU (41.1%), while EIP was most common with IU (71.2%).

摘要

目的

评估不同类型葡萄膜炎患者眼内压升高(EIP)和青光眼的患病率及临床病程。

材料与方法

对2003年1月至2023年1月在伊兹密尔埃杰大学眼科接受任何类型葡萄膜炎治疗的患者进行回顾性病历审查。纳入初次检查时已在用抗青光眼药物治疗、眼压(IOP)有短暂/持续升高或随访期间被诊断为青光眼的患者。记录人口统计学特征、葡萄膜炎类型、葡萄膜炎与青光眼/EIP诊断之间的时间、葡萄膜炎的局部和全身治疗以及抗青光眼药物和手术情况。

结果

共审查了2176份患者档案(1206例前葡萄膜炎[AU]、247例中间葡萄膜炎[IU]、165例后葡萄膜炎[PU]、558例全葡萄膜炎[PanU]),440例(20.2%)患者的594只眼(205例女性,235例男性)纳入研究(292只眼为AU、80只眼为IU、44只眼为PU、178只眼为PanU)。观察到220只眼(37.0%)患有青光眼,374只眼(63.0%)存在EIP。120只眼的AU、23只眼的IU、13只眼的PU和64只眼的PanU患有青光眼。458只眼(77.1%)通过药物治疗眼压得到控制,113只眼(19.0%)需要进行青光眼手术/激光治疗。23只眼(3.9%)无需治疗。

结论

青光眼/EIP的患病率为20.3%。青光眼在AU眼中最为常见(41.1%),而EIP在IU眼中最为常见(71.2%)。

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Safety and efficacy of intravitreal dexamethasone implantation along with phacoemulsification and intraocular lens implantation in children with uveitis.玻璃体内注射地塞米松植入联合超声乳化白内障吸除及人工晶状体植入术在儿童葡萄膜炎患者中的安全性和有效性
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