de Lumley L, Denis F, Boulesteix J, Bouquier J J, Boniface C
Arch Fr Pediatr. 1985 Aug-Sep;42(7):521-4.
Soluble antigens were looked for in 31 cases of purulent meningitis in children aged one day to 16 years. The latex technique was used in this study. Negative cases were controlled by counter-immune electrophoresis and by ELISA. From the results of our study and after a review of the literature, it appears that the latex technique is the best method at present to identify soluble antigens in purulent meningitis. This technique is better than a direct microscopic examination (p less than 0.02), especially in cases of meningitis due to H. influenzae and to S. pneumoniae. Latex technique kits used in the identification of type B meningococcus should be improved, and additional kits are needed if a wider range of bacteria are to be identified.
对31例年龄在1天至16岁的儿童化脓性脑膜炎病例进行了可溶性抗原检测。本研究采用乳胶技术。阴性病例通过反向免疫电泳和酶联免疫吸附测定进行对照。从我们的研究结果以及文献综述来看，乳胶技术似乎是目前鉴定化脓性脑膜炎中可溶性抗原的最佳方法。该技术比直接显微镜检查更好（p<0.02），尤其是在由流感嗜血杆菌和肺炎链球菌引起的脑膜炎病例中。用于鉴定B型脑膜炎球菌的乳胶技术试剂盒应加以改进，如果要鉴定更广泛的细菌种类，则还需要其他试剂盒。
