Miyashita N, Moriwaki K, Minezawa M, Yonekawa H, Bonhomme F, Migita S, Yu Z C, Lu D Y, Cho W S, Thohari M
Biochem Genet. 1985 Dec;23(11-12):975-86. doi: 10.1007/BF00499941.
We studied the allelic frequency of the hemoglobin beta chain (Hbb) of wild mice, Mus musculus, collected from 46 localities, mostly in Asia and surrounding areas. The wild populations in the northern part of China, Korea, and the central part of Japan exhibited an almost monomorphic distribution of Hbbp. In the southern part of Asia, the frequency of Hbbp decreased and Hbbd was predominant. Although Hbbs and Hbbd are generally found in Europe, the Hbbp allele was present in Southeastern Europe (Bulgaria). In the light of these results, the Hbbp allele might have originated in mice of northern Asia.
我们研究了从46个地点收集的野生小家鼠血红蛋白β链（Hbb）的等位基因频率，这些地点大多位于亚洲及周边地区。中国北部、韩国和日本中部的野生种群呈现出Hbbp几乎单态的分布。在亚洲南部，Hbbp的频率降低，Hbbd占主导地位。虽然Hbbs和Hbbd在欧洲普遍存在，但Hbbp等位基因存在于东南欧（保加利亚）。根据这些结果，Hbbp等位基因可能起源于亚洲北部的小鼠。
