Chen Yao, Chen Feng, Luo Ye-Xin, Xiong Lin
Radiation Therapy Center, Chongqing University Cancer Hospital, Chongqing 400030, P.R. China.
Pre-Hospital Emergency Department, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, P.R. China.
Oncol Lett. 2025 Aug 7;30(4):471. doi: 10.3892/ol.2025.15217. eCollection 2025 Oct.
The present study aimed to investigate whether red blood cell distribution width (RDW) was an independent prognosis factor for patients with glioma after surgery. Potential studies were found in four databases including PubMed, Embase, China National Knowledge Infrastructure and the Cochrane Library on 21st July, 2022. To evaluate the prognosis after surgery, hazard ratios (HRs) and 95% confidence intervals (CIs) were pooled to calculate the overall survival (OS) of patients with glioma. Stata V16.0 software was used for data analysis. A total of 8 studies were included, involving 1,468 patients. After collecting and analyzing the data, RDW was demonstrated to be a prognostic factor for OS of patients with glioma (HR=1.51; I=0.00%; 95% CI, 1.29-1.74; P<0.01). Patients with high preoperative RDW levels had a high risk of poor survival after neurosurgery. High preoperative RDW levels may be associated with poor prognosis and warrant further clinical attention.
本研究旨在探讨红细胞分布宽度（RDW）是否为胶质瘤患者术后的独立预后因素。于2022年7月21日在包括PubMed、Embase、中国知网和考克兰图书馆在内的四个数据库中检索相关研究。为评估术后预后，汇总风险比（HR）和95%置信区间（CI）以计算胶质瘤患者的总生存期（OS）。采用Stata V16.0软件进行数据分析。共纳入8项研究，涉及1468例患者。在收集和分析数据后，RDW被证明是胶质瘤患者OS的预后因素（HR=1.51；I=0.00%；95%CI，1.29-1.74；P<0.01）。术前RDW水平高的患者神经外科手术后生存不良风险高。术前RDW水平高可能与预后不良相关，值得临床进一步关注。
