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第四脑室术后微囊性脑膜瘤伴随后续的巨细胞修复性肉芽肿:一例报告

Postoperative microcystic meningioma of the fourth ventricle with subsequent giant cell reparative granuloma: a case report.

作者信息

Xu Fangfang, Fu Chengzhi, Li Qian, Dong Fei, Tang Jinlong, Wang Chao, Sun Chongran

机构信息

Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Department of Radiology, The First Affiliated Hospital, Three Gorges University School of Medicine, Yichang, China.

出版信息

Front Oncol. 2025 Aug 6;15:1624498. doi: 10.3389/fonc.2025.1624498. eCollection 2025.

Abstract

BACKGROUND

Microcystic meningioma (MM) is a distinctive benign tumor typically located in the supratentorial region. Giant cell reparative granuloma (GCRG) is another rare reactive benign lesion associated with surgical trauma or tissue injury. The occurrence of MM in the fourth ventricle is extremely uncommon, and the development of GCRG following cranial tumor surgery is rare. We present a case of MM extending into the fourth ventricle in a 54-year-old man. The initial diagnosis was based on magnetic resonance imaging (MRI), and the tumor was successfully treated with surgery. Postoperative histopathological analysis confirmed the diagnosis of MM. However, a mass was detected at the original surgical site during a follow-up examination one year later. Combined preoperative imaging and postoperative pathology confirmed the final diagnosis of giant cell reparative granuloma (GCRG).

CONCLUSION

In cases of MM at atypical locations and GCRG, an imaging-based differential diagnosis is crucial for guiding treatment decisions and predicting prognosis. Regular postoperative reviews are also essential for detecting complications.

摘要

背景

微囊性脑膜瘤(MM)是一种独特的良性肿瘤,通常位于幕上区域。巨细胞修复性肉芽肿(GCRG)是另一种与手术创伤或组织损伤相关的罕见反应性良性病变。MM发生于第四脑室极为罕见,且颅骨肿瘤手术后发生GCRG也很罕见。我们报告一例54岁男性MM延伸至第四脑室的病例。最初诊断基于磁共振成像(MRI),肿瘤通过手术成功治疗。术后组织病理学分析确诊为MM。然而,一年后的随访检查中在原手术部位发现一个肿块。结合术前影像学和术后病理确诊为巨细胞修复性肉芽肿(GCRG)。

结论

对于非典型部位的MM和GCRG病例,基于影像学的鉴别诊断对于指导治疗决策和预测预后至关重要。术后定期复查对于发现并发症也必不可少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bc7/12364659/7a232ba50a4d/fonc-15-1624498-g001.jpg

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