Yan Bo, Lu Mengjiao, Han Jijing, Cao Yuhao, Yan Fei, Song Xuemei
State Key Laboratory for Quality and Safety of Agro-products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Ningbo University, Ningbo, China.
Front Microbiol. 2025 Aug 6;16:1655696. doi: 10.3389/fmicb.2025.1655696. eCollection 2025.
Strawberry ( × Duch.) production is threatened by more than 20 viral pathogens, which frequently occur in mixed infections, leading to significant yield losses and diagnostic complexities. This review summarizes recent advances in the biology and molecular biology of the major strawberry-infecting viruses, strawberry vein banding virus, strawberry necrotic shock virus, strawberry mottle virus, strawberry latent ringspot virus, strawberry mild yellow edge virus, strawberry pallidosis-associated virus, and strawberry polerovirus 1. It reviews the molecular interactions between viruses and strawberry and also highlights cutting-edge detection technologies, including high-throughput sequencing, RT-PCR/qPCR, and isothermal amplification coupled with lateral flow assays. Despite these advances, critical research gaps remain, particularly in the functional characterization of viral proteins, the mechanisms underlying synergistic and antagonistic interactions in mixed infections, and the development of rapid, field-deployable diagnostic tools. Addressing these challenges is essential for enhancing virus-free certification programs, guiding targeted breeding efforts, and implementing effective disease management strategies to ensure the sustainability of global strawberry production.
草莓（× 杜氏）生产受到20多种病毒病原体的威胁，这些病原体经常混合感染，导致产量大幅损失和诊断复杂性增加。本综述总结了主要感染草莓的病毒，如草莓脉带病毒、草莓坏死休克病毒、草莓斑驳病毒、草莓潜隐环斑病毒、草莓轻型黄边病毒、草莓苍白病相关病毒和草莓马铃薯Y病毒1在生物学和分子生物学方面的最新进展。它回顾了病毒与草莓之间的分子相互作用，还重点介绍了前沿检测技术，包括高通量测序、RT-PCR/qPCR以及与侧流分析相结合的等温扩增。尽管取得了这些进展，但关键的研究空白仍然存在，特别是在病毒蛋白的功能表征、混合感染中协同和拮抗相互作用的潜在机制以及快速、可在田间部署的诊断工具的开发方面。应对这些挑战对于加强无病毒认证计划、指导定向育种工作以及实施有效的疾病管理策略以确保全球草莓生产的可持续性至关重要。
