Napole Alan, Sioutas Georgios, Davis Pierce, Reddy Chethan, Patel Saarang, Kandregula Sandeep, Mannam Sneha S, Jabarkheel Rashad, Scott Kyle W, Shekhtman Oleg, Burkhardt Jan-Karl, Srinivasan Visish M
Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Cureus. 2025 Aug 20;17(8):e90577. doi: 10.7759/cureus.90577. eCollection 2025 Aug.
Background Advancements in neuroendovascular surgery with sophisticated catheters have enhanced outcomes in complex procedures. The FDA-approved Vecta46 intermediate catheter (IMC) by Stryker Corporation (Kalamazoo, MI) is used in various neurovascular interventions. Since its approval, the Vecta46 IMC has not been comprehensively studied. This study evaluates its safety, versatility, and efficacy in real-world multi-pathology applications. Methods We retrospectively reviewed 53 patients who underwent endovascular procedures with the Vecta46 IMC. We collected and analyzed demographic details, baseline characteristics, procedural specifics, and clinical outcomes. Results Among 53 cases, common comorbidities included hypertension (n = 25, 47.2%) and hyperlipidemia (n = 22, 41.5%). Antiplatelet use was noted in 43.4% (n = 23), and anticoagulant use in 13.2% (n = 7). Aneurysm treatments accounted for 56.6% (n = 30) of cases, followed by middle meningeal artery (MMA) embolization for chronic subdural hematomas (cSDHs) (18.9%) (n = 10), stroke thrombectomies (11.3%) (n = 6), Onyx embolization for dural arteriovenous fistulas (dAVFs) (7.5%) (n = 4), and arteriovenous malformations (AVMs) (5.7%) (n = 3). Flow diversion was the most common aneurysm treatment (56.7%) (n = 17). Most procedures were transradial (79.2%) (n = 42), primarily on the right side (88.7%) (n = 47), with verapamil used in 75.5% (n = 40). The mean number of vessels selected was 3.2±1.9, procedure duration was 102.4±66.8 minutes, fluoroscopy time was 43.6±31.1 minutes, contrast dose was 80.5±31.6 mL, and reference air kerma was 2114.0±1349.4 mGy. The Vecta46 was successfully navigated to the target vessel in 96.2% (n = 51) of cases. Intraprocedural complications included a nontarget vessel embolization, a thromboembolic event, and a non-flow-limiting focal dissection. No hemorrhagic complications or vessel irregularities occurred in the Vecta46 region. Post-procedural complications were minimal, with only forearm edema and an access site hematoma. Conclusions The Vecta46 catheter is an effective and safe tool for endovascular procedures, demonstrating versatility and reliability in neurovascular interventions.
背景 先进的神经血管内手术及精密导管提高了复杂手术的成功率。史赛克公司(密歇根州卡拉马祖)生产的经美国食品药品监督管理局(FDA)批准的Vecta46中间导管(IMC)用于各种神经血管介入手术。自获批以来,尚未对Vecta46 IMC进行全面研究。本研究评估其在实际多病理应用中的安全性、多功能性和有效性。方法 我们回顾性分析了53例行Vecta46 IMC血管内手术的患者。收集并分析了人口统计学细节、基线特征、手术细节和临床结果。结果 53例患者中,常见合并症包括高血压(n = 25,47.2%)和高脂血症(n = 22,41.5%)。43.4%(n = 23)的患者使用了抗血小板药物,13.2%(n = 7)的患者使用了抗凝剂。动脉瘤治疗占病例的56.6%(n = 30),其次是用于慢性硬膜下血肿(cSDH)的脑膜中动脉(MMA)栓塞(18.9%)(n = 10)、中风血栓切除术(11.3%)(n = 6)、用于硬脑膜动静脉瘘(dAVF)的Onyx栓塞(7.5%)(n = 4)和动静脉畸形(AVM)(5.7%)(n = 3)。血流导向是最常见的动脉瘤治疗方法(56.7%)(n = 17)。大多数手术经桡动脉进行(79.2%)(n = 42),主要在右侧(88.7%)(n = 47),75.5%(n = 40)的患者使用了维拉帕米。所选血管的平均数量为3.2±1.9条,手术时间为102.4±66.8分钟,透视时间为43.6±31.1分钟,造影剂剂量为80.5±31.6 mL,参考空气比释动能为2114.0±1349.