Gantuya Boldbaatar, Inoue Haruhiro, Yamamoto Kazuki, Tanaka Ippei, Nishikawa Yohei, Ushikubo Kei, Tanabe Mayo
Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
Department of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
VideoGIE. 2025 May 2;10(9):443-447. doi: 10.1016/j.vgie.2025.04.011. eCollection 2025 Sep.
Zenker's diverticulum (ZD) is a pouch of the mucosa arising from the Killian triangle. Any size of symptomatic ZD or medium to large (2-3 cm or more) ZD needs intervention. Zenker's peroral endoscopic myotomy (Z-POEM) is the ideal first-line therapy for making the reliable myotomy. We aimed to demonstrate the latest Z-POEM techniques and counter mucosal incision (CMI) for a patient with larger-sized ZD and pre-existing esophageal mucosal webs near ZD.
The CMI technique recently was developed by our hospital for antireflux intervention. It is a novel tension-relief technique of the mucosal plasty for enhancing closure stability. This time we performed esophageal mucosal incision on the opposite side of the Z-POEM defect closure part to relieve the mucosal tension and alleviate a postoperative stricture resulting from the tight clip closure in the background of the stiff surrounding mucosa and webs near the ZD.
We obtained complete eradication of ZD pouch without creating a stricture.
CMI is the ideal approach for preventing a stricture related to the use of tight clip closure of the Z-POEM for a larger-sized ZD with a background of the surrounding mucosal webs.
Zenker憩室(ZD)是一种起源于Killian三角区的黏膜袋。任何有症状的ZD或中至大型(2 - 3厘米或更大)ZD都需要干预。Zenker经口内镜下肌切开术(Z-POEM)是进行可靠肌切开术的理想一线治疗方法。我们旨在展示针对一名患有较大尺寸ZD且ZD附近存在食管黏膜蹼的患者的最新Z-POEM技术及对抗黏膜切口(CMI)。
CMI技术是我院最近开发的用于抗反流干预的技术。它是一种新型的黏膜成形术张力缓解技术,可增强闭合稳定性。此次我们在Z-POEM缺损闭合部位的对侧进行食管黏膜切开,以缓解黏膜张力,并减轻在ZD周围黏膜僵硬和蹼的背景下因紧密夹闭导致的术后狭窄。
我们实现了ZD袋的完全根除且未造成狭窄。
对于周围有黏膜蹼背景的较大尺寸ZD,CMI是预防与Z-POEM紧密夹闭相关狭窄的理想方法。