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C反应蛋白与白蛋白联合指数在预测急性心力衰竭患者插管需求中的作用:一项前瞻性观察研究。

The role of C-reactive protein and albumin combined ındexes in predicting the need for ıntubation in acute heart failure: A prospective observational study.

作者信息

Algin Abdullah, Ozkan Abuzer, Yusufoglu Kaan, Ozdemir Serdar, Afacan Mustafa Ahmet

机构信息

Department of Emergency Medicine, University of Health of Sciences, Umraniye Training and Research Hospital, Istanbul, Turkiye.

Department of Emergency Medicine, University of Health of Sciences, Bagcilar Training and Research Hospital, Istanbul, Turkiye.

出版信息

North Clin Istanb. 2025 Jun 18;12(3):314-320. doi: 10.14744/nci.2025.76032. eCollection 2025.

Abstract

OBJECTIVE

Heart failure is a clinical syndrome, caused by functional or structural dysfunction of the heart. Taking early decisions for interventional procedures and predicting the treatment process will be beneficial for patients and will shorten the waiting times for the emergency department. We evaluated the capability of C-reactive protein (CRP) and albumin combined indexes to predict the need for intubation in acute heart failure.

METHODS

This study was designed prospectively. Patients with signs and symptoms such as weakness, shortness of breath, abnormal findings in lung sounds, jugular fullness, peripheral edema, and ankle swelling at the time of admission were evaluated. All patients were diagnosed with acute heart failure in the Emergency Department (ED).

RESULTS

A total of 220 patients were included. The median age was 77. CRP Albumin Ratio (CAR) was higher in the intubated group. Glasgow Prognostic Score (GPS) and modified Glasgow Prognostic Score (mGPS) sensitivity, specificity, accuracy and other values were the same.

CONCLUSION

These scores, which are simple and do not require additional examination, can be used to predict the clinical progress of patients.

摘要

目的

心力衰竭是一种临床综合征,由心脏功能或结构功能障碍引起。尽早决定介入治疗程序并预测治疗过程将对患者有益,并将缩短急诊科的等待时间。我们评估了C反应蛋白(CRP)和白蛋白联合指标预测急性心力衰竭患者插管需求的能力。

方法

本研究为前瞻性设计。对入院时出现虚弱、呼吸急促、肺部听诊异常、颈静脉充盈、外周水肿和脚踝肿胀等症状和体征的患者进行评估。所有患者均在急诊科(ED)被诊断为急性心力衰竭。

结果

共纳入220例患者。中位年龄为77岁。插管组的CRP白蛋白比值(CAR)较高。格拉斯哥预后评分(GPS)和改良格拉斯哥预后评分(mGPS)的敏感性、特异性、准确性等数值相同。

结论

这些评分简单,无需额外检查,可用于预测患者的临床进展。

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