Babelay Gaurav, Ahmad Ahsan, Ranjan Nikhil, Dheeraj Kumar
Department of Urology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
Urol Ann. 2025 Jul-Sep;17(3):156-160. doi: 10.4103/ua.ua_121_24. Epub 2025 Jul 18.
It was estimated that 3%-8% of women presented with bladder obstruction, and 4%-13% of these women had female urethral stricture (FUS), which is an uncommon disorder.
The study has been conducted to analyze the outcome of Dorsal onlay urethroplasty using buccal mucosal graft (BMG) and vaginal wall graft (VWG) for FUS.
It was a retrospective, single-centric cohort study. The study has been conducted for 2 years and 2 months, i.e., from July 2021 to September 2023.
The study included 20 female patients with urethral stricture who had urethroplasty. The participants were further classified into two groups respectively. One of the groups included 10 participants with cases of BMG urethroplasty and another 10 were cases of VWG urethroplasty.
The Statistical Package for the Social Sciences (SPSS) version 24 program was used to analyze the data. Both continuous and categorical variables were present in the data. Descriptive Statistics were expressed as mean ± standard deviation or (%) or .
The BMG group had a substantially lower postvoid residual (PVR) of 10 ± 4.2 mL than the VWG group, which had a PVR of 15 ± 6.4 mL with a = 0.04. The operating time was 110 ± 10.8 in the BMG urethroplasty group and 90 ± 8.2 in the VWG group with a < 0.001. VWG urethroplasty group. No statistically significant differences were observed in terms of AUA symptom score and Q.
The study concluded that FUS reconstruction can offer a good, long-lasting response. Moreover, between both the preferred techniques of BMG and VWG urethroplasty, which is safe and effective, patients with postmenopausal atrophy or vaginal pathology may benefit more from BMG.
据估计,3% - 8%的女性存在膀胱梗阻,其中4% - 13%的女性患有女性尿道狭窄(FUS),这是一种罕见的疾病。
本研究旨在分析使用颊黏膜移植物(BMG)和阴道壁移植物(VWG)进行背侧覆盖尿道成形术治疗FUS的效果。
这是一项回顾性、单中心队列研究。研究持续了2年2个月,即从2021年7月至2023年9月。
该研究纳入了20例接受尿道成形术的女性尿道狭窄患者。参与者被进一步分为两组。其中一组包括10例接受BMG尿道成形术的患者,另一组10例为VWG尿道成形术患者。
使用社会科学统计软件包(SPSS)24版程序分析数据。数据中既有连续变量也有分类变量。描述性统计以均值±标准差或(%)表示。
BMG组的排尿后残余尿量(PVR)显著低于VWG组,分别为10±4.2 mL和15±6.4 mL,P = 0.04。BMG尿道成形术组的手术时间为110±10.8分钟,VWG组为90±8.2分钟,P < 0.001。在AUA症状评分和Q方面,未观察到统计学上的显著差异。
该研究得出结论,FUS重建可提供良好的长期效果。此外,在BMG和VWG尿道成形术这两种首选技术中,二者均安全有效,绝经后萎缩或阴道病变的患者可能从BMG中获益更多。