Ümraniye Training and Research Hospital, Clinic of Urology, Istanbul, Turkey.
Department of Urology, Bezmi Alem Vakıf University Hospital, Istanbul, Turkey.
Urology. 2014 Feb;83(2):460-4. doi: 10.1016/j.urology.2013.09.020. Epub 2013 Nov 7.
To evaluate the functional outcomes of ventral inlay labia minora graft urethroplasty (VILGU) for the management of female urethral strictures.
Data of 7 consecutive women treated with VILGU between 2011 and 2013 were reviewed. Two patients had cystostomy tubes at repair, and 5 had undergone previous urethral dilations and urethrotomies. Clinical evaluation included assessment of the effect of voiding symptoms with American Urological Association (AUA) symptom score, uroflowmetry, voiding cystourethrography, and intraoperative urethrocystoscopy using a 6.5F pediatric ureterorenoscope. Preoperative AUA symptom score and peak urinary flow rate were compared with postoperative values. Cure was defined as the absence of any restenosis requiring additional intervention with subjective patient satisfaction at the last follow-up.
Mean stricture length was 1.5 cm (range, 1-2.5), and mean operative time was 95 minutes (range, 70-110). With a mean follow-up of 18.2 months (range, 3-30), cure was achieved in 6 (86%) women. At the last follow-up, mean maximum urine flow (mL/s) increased from 3.9 ± 3.1 preoperatively to 22.7 ± 8.3 postoperatively (P <.001), and mean AUA symptom score decreased from 25.3 ± 5.2 preoperatively to 6.9 ± 3.7 postoperatively (P = .001). No fistulae developed after surgery. "De-novo" stress urinary incontinence was not evident in any case.
VILGU effectively provides better urinary flow and significantly improves patient satisfaction in patients with female urethral stricture disease.
评估采用阴唇皮瓣下置尿道成形术(VILGU)治疗女性尿道狭窄的功能结局。
回顾了 2011 年至 2013 年间接受 VILGU 治疗的 7 例连续女性患者的数据。2 例患者在修复时留置了膀胱造瘘管,5 例患者曾接受过尿道扩张和尿道切开术。临床评估包括采用美国泌尿外科学会(AUA)症状评分、尿流率、排尿性膀胱尿道造影和使用 6.5F 小儿输尿管镜进行术中尿道膀胱镜检查来评估排尿症状的效果。比较了术前和术后的 AUA 症状评分和最大尿流率。治愈定义为无任何再狭窄,不需要额外干预,且最后一次随访时患者主观满意度高。
平均狭窄长度为 1.5cm(范围,1-2.5cm),平均手术时间为 95 分钟(范围,70-110 分钟)。平均随访 18.2 个月(范围,3-30 个月),6 例(86%)女性患者获得治愈。最后一次随访时,最大尿流率(mL/s)从术前的 3.9 ± 3.1 增加到术后的 22.7 ± 8.3(P<.001),AUA 症状评分从术前的 25.3 ± 5.2 降低到术后的 6.9 ± 3.7(P=.001)。术后无瘘管形成。在任何情况下均未出现“新发”压力性尿失禁。
VILGU 可有效提供更好的尿流,并显著提高女性尿道狭窄患者的满意度。