通过对乙酰氨基酚吸收法和内镜检查法研究胰高血糖素对胃动力的影响。
Effect of glucagon on gastric motility examined by the acetaminophen absorption method and the endoscopic procedure.
作者信息
Kawamoto H, Yamamura H, Tatsuta M, Okuda S
出版信息
Arzneimittelforschung. 1985;35(9):1475-7.
The effects of glucagon and butropium bromide on gastric motility were compared by the acetaminophen absorption method and the endoscopic procedure. Intramuscular administration of 1 USP unit of glucagon and 4 mg of butropium bromide caused a significant decrease in the serum acetaminophen level 30 min after digestion of a test meal. Results indicated that glucagon significantly delayed gastric emptying, and that its inhibitory effect was similar to that of butropium bromide. Moreover, endoscopic examinations showed that glucagon and butropium bromide had similar inhibitory effects on gastric peristalsis. However, butropium bromide caused side effects more frequently than glucagon. Therefore, premedication with glucagon is superior to that with butropium bromide for upper gastrointestinal endoscopy.
通过对乙酰氨基酚吸收法和内镜检查法比较了胰高血糖素和溴化丁基东莨菪碱对胃动力的影响。肌肉注射1美国药典单位的胰高血糖素和4毫克溴化丁基东莨菪碱，在试餐消化30分钟后导致血清对乙酰氨基酚水平显著下降。结果表明，胰高血糖素显著延迟胃排空，其抑制作用与溴化丁基东莨菪碱相似。此外，内镜检查显示，胰高血糖素和溴化丁基东莨菪碱对胃蠕动有相似的抑制作用。然而，溴化丁基东莨菪碱比胰高血糖素更频繁地引起副作用。因此，在上消化道内镜检查中，使用胰高血糖素进行预处理优于使用溴化丁基东莨菪碱。
Zotero 插件