胃底胃炎和胃癌患者的胃排空情况。
Gastric emptying in patients with fundal gastritis and gastric cancer.
作者信息
Tatsuta M, Iishi H, Okuda S
机构信息
Department of Gastrointestinal Oncology, Centre for Adult Diseases, Osaka, Japan.
出版信息
Gut. 1990 Jul;31(7):767-9. doi: 10.1136/gut.31.7.767.
Gastric emptying was compared in patients with gastric cancers and fundal gastritis to determine its value in identifying patients at high risk of gastric cancer. Gastric emptying was measured by the acetaminophen absorption method, and the extent of fundal gastritis was determined by the endoscopic Congo red test. The results showed that gastric emptying was significantly slower in patients with severe fundal gastritis than in those without. Gastric emptying in patients with differentiated adenocarcinomas was significantly slower than in those with undifferentiated adenocarcinoma, its value being similar to that in patients with severe fundal gastritis. The Congo red test showed that the incidence of severe fundal gastritis was significantly greater in patients with differentiated adenocarcinomas than in those with undifferentiated cancers. These findings suggest that delayed gastric emptying may allow prolonged contact between dietary carcinogens and the stomach.
对胃癌患者和胃底胃炎患者的胃排空情况进行比较，以确定其在识别胃癌高危患者中的价值。采用对乙酰氨基酚吸收法测量胃排空情况，并通过内镜刚果红试验确定胃底胃炎的程度。结果显示，重度胃底胃炎患者的胃排空明显比无胃底胃炎患者慢。分化型腺癌患者的胃排空明显比未分化腺癌患者慢，其情况与重度胃底胃炎患者相似。刚果红试验显示，分化型腺癌患者中重度胃底胃炎的发生率明显高于未分化癌患者。这些发现表明，胃排空延迟可能会使膳食致癌物与胃的接触时间延长。
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