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2022年至2025年7月期间,在德国和波兰的ST-574疫情中出现了两例本地白喉病例的亚群。

Two diphtheria sub-clusters with autochthonous cases in Germany and Poland within a ST-574 outbreak, 2022 to July 2025.

作者信息

Roewer de Porto Imme Friederike, Dangel Alexandra, Schneider Lena, Zasada Aleksandra A, Haller Jonas, Abdelgawad Inas, Siffczyk Claudia, Paradowska-Stankiewicz Iwona, Wichmann Ole, Badenschier Franziska, Berger Anja, Rau Cornelius, Sing Andreas

机构信息

These authors contributed equally to this work and share first/last authorship.

ECDC Fellowship Programme, Field Epidemiology path (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

出版信息

Euro Surveill. 2025 Aug;30(33). doi: 10.2807/1560-7917.ES.2025.30.33.2500539.

DOI:10.2807/1560-7917.ES.2025.30.33.2500539
PMID:40843519
Abstract

Within a ST-574 outbreak comprising mostly migration-associated cases since 2022, Germany detected two sub-clusters in 2025. Among sub-cluster cases with travel information (24/26), 22 were acquired autochthonously. One of two imported cases came from a Polish voivodeship having an additional case. Sub-cluster 1 included 16 cutaneous cases, sub-cluster 2 included six cutaneous and five respiratory cases. One unvaccinated child and two older adults died. Of 27 cases, 12 experienced homelessness. Strengthened immunisation, improved wound care and international surveillance are needed.

摘要

在自2022年以来主要由与移民相关的病例组成的ST-574疫情中,德国在2025年发现了两个子集群。在有旅行信息的子集群病例中(26例中的24例),22例是本地感染的。两例输入性病例中的一例来自波兰的一个省,该省还有一例病例。子集群1包括16例皮肤病例,子集群2包括6例皮肤病例和5例呼吸道病例。一名未接种疫苗的儿童和两名老年人死亡。27例病例中有12例无家可归。需要加强免疫、改善伤口护理和国际监测。

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本文引用的文献

1
Autochthonous outbreak of respiratory diphtheria caused by , Germany, September 2024.2024年9月,德国发生由[病原体未提及]引起的呼吸道白喉本地暴发。
Euro Surveill. 2025 Jul;30(27). doi: 10.2807/1560-7917.ES.2025.30.27.2500116.
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Outbreak in Migrant Populations in Europe.欧洲移民群体中的疫情爆发。
N Engl J Med. 2025 Jun 19;392(23):2334-2345. doi: 10.1056/NEJMoa2311981. Epub 2025 Jun 4.
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A case of fatal respiratory diphtheria imported from Poland to Germany: possible link to an undetected imported diphtheria cluster in Poland?
一例从波兰输入德国的致命性呼吸道白喉病例:是否与波兰一个未被发现的输入性白喉聚集性病例有关?
Infection. 2025 Apr 2. doi: 10.1007/s15010-025-02522-y.
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Diphtheria Outbreak among Persons Experiencing Homelessness, 2023, Linked to 2022 Diphtheria Outbreak, Frankfurt am Main, Germany.2023年德国美因河畔法兰克福无家可归者中的白喉疫情,与2022年白喉疫情有关。
Emerg Infect Dis. 2025 Mar;31(3):547-554. doi: 10.3201/eid3103.241217.
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Toxigenic Corynebacterium diphtheriae Infections in Low-Risk Patients, Switzerland, 2023.2023年瑞士低风险患者中的产毒白喉棒状杆菌感染
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