Steinbichler Teresa Bernadette, Bender Birte, Hartl Roland, Strasser Verena, Sontheimer Daniel, Buricic Sladjana, Kofler Barbara, Högl Birgit, Riechelmann Herbert, Hofauer Benedikt
Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Department of Neurology, Sleep Disorders Clinic, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Clocks Sleep. 2025 Jul 29;7(3):38. doi: 10.3390/clockssleep7030038.
Uvulopalatopharyngoplasty (UPPP) and expansion sphincter pharyngoplasty (ESP) are two standard surgical procedures for the treatment of snoring and obstructive sleep apnea. In a retrospective clinical trial, we compared the two surgical techniques regarding objective sleep parameters and patients' reported outcomes.
Patients treated with UPPP or ESP between January 2016 and February 2020 were included in this retrospective clinical trial. Pre- and postoperative AHI, BMI, and smoking habits were recorded. Subjective improvement was assessed by the ESS score and symptom relief reported by patients and their bed partners.
Between 2016 and 2020, 114 patients were included in the study, 74 patients suffered from OSA, and 30 patients had non-apnoeic snoring (AHI < 5/h). No preoperative sleeping studies were available in 10 patients (10/114; 9%). Based on the findings during drug-induced sedation endoscopy, most patients received an ESP (71/114, 62%), and 43 patients received a UPPP (43/114, 38%). Additionally, in 52/114 (46%), radio frequency ablation of the tongue base was performed if DISE revealed retrolingual collapse. ESP reduced AHI from 21.1 ± 10.8/h to 13.3 ± 12.1/h ( = 0.04), whereas UPPP caused a non-significant decrease in the AHI from 25.0 ± 13.8/h to 18.2 ± 14.6/h ( = 0.6). A minor secondary bleeding was observed in 32 patients, which was effectively treated with electrocautery or conservative therapy (32/114). This was more common in the ESP group (22/71; 31%) than in the UPPP group (10/43; 23%). Postoperative need for analgesics was higher in the ESP group than in the UPPP group. The ESS score showed no significant improvement after UPPP or ESP ( = 0.3), but subjective improvement in snoring was reported by 87/114 (76%) patients.
AHI reduction was significantly higher in the ESP patient group than in the UPPP group. ESP patients had a slightly higher rate of minor secondary bleeding and postoperative need for analgesics than UPPP patients.
悬雍垂腭咽成形术(UPPP)和扩约肌咽成形术(ESP)是治疗打鼾和阻塞性睡眠呼吸暂停的两种标准外科手术。在一项回顾性临床试验中,我们比较了这两种外科技术在客观睡眠参数和患者报告结局方面的差异。
本回顾性临床试验纳入了2016年1月至2020年2月期间接受UPPP或ESP治疗的患者。记录术前和术后的呼吸暂停低通气指数(AHI)、体重指数(BMI)和吸烟习惯。通过Epworth嗜睡量表(ESS)评分以及患者及其同床伴侣报告的症状缓解情况评估主观改善情况。
2016年至2020年期间,114例患者纳入研究,其中74例患有阻塞性睡眠呼吸暂停(OSA),30例患有非呼吸暂停性打鼾(AHI<5次/小时)。10例患者(10/114;9%)术前未进行睡眠研究。根据药物诱导镇静内镜检查结果,大多数患者接受了ESP手术(71/114,62%),43例患者接受了UPPP手术(43/114,38%)。此外,在52/114(46%)的患者中,如果药物诱导镇静内镜检查显示舌根后坠,则进行舌根射频消融术。ESP组患者的AHI从21.1±10.8次/小时降至13.3±12.1次/小时(P = 0.04),而UPPP组患者的AHI从25.0±13.8次/小时降至18.2±14.6次/小时,差异无统计学意义(P = 0.6)。32例患者出现轻微继发性出血,通过电灼或保守治疗有效处理(32/114)。这在ESP组(22/71;31%)比UPPP组(10/43;23%)更常见。ESP组术后镇痛药物需求高于UPPP组。UPPP或ESP术后ESS评分无显著改善(P = 0.3),但114例患者中有87例(76%)报告打鼾有主观改善。
ESP患者组AHI降低幅度显著高于UPPP组。ESP患者轻微继发性出血发生率和术后镇痛药物需求率略高于UPPP患者。