Department of 'Organi Di Senso', University "Sapienza", Viale Università 33, 00185, Rome, Italy.
Department ENT & Audiology, University of Ferrara, Ferrara, Italy.
Sleep Breath. 2024 Dec;28(6):2601-2616. doi: 10.1007/s11325-024-03162-6. Epub 2024 Sep 23.
Upper airway (UA) surgery is commonly employed in the treatment of patients with obstructive sleep apnea (OSA). The intricate pathophysiology of OSA, variability in sites and patterns of UA collapse, and the interaction between anatomical and non-anatomical factors in individual patients may contribute to possible surgical failures. This clinical consensus statement aims to identify areas of agreement among a development group comprising international experts in OSA surgery, regarding the appropriate definition, predictive factors in patients, and management of surgical failure in OSA treatment.
A clinical consensus statement (CCS) was developed using the Delphi method by a panel of 35 contributors from various countries. A systematic literature review adhering to PRISMA guidelines was conducted. A survey consisting of 60 statements was then formulated and presented to the experts.
Following two rounds of the Delphi process, consensus or strong consensus was achieved on 36 items, while 24 items remained without consensus. Specifically, 5 out of 10 statements reached consensus regarding on the 'Definition of Surgical Success/Failure after OSA Surgery'. Regarding the 'Predictive Factors of Surgical Failure in OSA Surgery', consensus was reached on 10 out of 13 statements. In the context of the 'Diagnostic Workup in OSA Surgery', consensus was achieved on 9 out of 13 statements. Lastly, in 'Treatment in Surgical Failure Cases', consensus was reached on 12 out of 24 statements.
The management of OSA after surgical failure presents a significant clinical challenge for sleep specialists. This CCS provides valuable guidance for defining, preventing, and addressing surgical failures in the treatment of OSA syndrome.
上呼吸道(UA)手术常用于治疗阻塞性睡眠呼吸暂停(OSA)患者。OSA 的复杂病理生理学、UA 塌陷部位和模式的可变性,以及个体患者中解剖和非解剖因素之间的相互作用,可能导致手术失败。本临床共识声明旨在确定由 OSA 手术国际专家组成的发展小组在适当定义、患者预测因素以及 OSA 治疗中手术失败管理方面的共识领域。
通过来自不同国家的 35 名贡献者组成的小组使用 Delphi 方法制定了临床共识声明(CCS)。按照 PRISMA 指南进行了系统的文献回顾。然后制定了一份包含 60 项陈述的调查,并提交给专家。
经过两轮 Delphi 流程,36 项达成共识或强烈共识,而 24 项仍未达成共识。具体来说,在 OSA 手术后关于“手术成功/失败的定义”的 10 项陈述中有 5 项达成共识。关于“OSA 手术中手术失败的预测因素”,13 项陈述中有 10 项达成共识。在“OSA 手术中的诊断工作”方面,13 项陈述中有 9 项达成共识。最后,在“手术失败病例的治疗”方面,24 项陈述中有 12 项达成共识。
手术失败后 OSA 的治疗对睡眠专家来说是一个重大的临床挑战。本 CCS 为定义、预防和解决 OSA 综合征治疗中的手术失败提供了有价值的指导。