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强脉冲光改善系统性红斑狼疮患者面部毛细血管扩张及痤疮所致炎症后红斑:一例报告

Intense Pulsed Light Improves Facial Telangiectasia and Acne-Induced Post-Inflammatory Erythema in Systemic Lupus Erythematosus Patient: A Case Report.

作者信息

Li Zhen, Lu Jiejie, Wu Miaoting

机构信息

Plastic and Cosmetic Center, The Fifth People's Hospital of Hainan Province, Haikou, Hainan Province, China.

出版信息

J Cosmet Dermatol. 2025 Aug;24(8):e70389. doi: 10.1111/jocd.70389.

Abstract

BACKGROUND

Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease. Standard treatment typically involves corticosteroids, antimalarials, and immunosuppressants; however, long-term corticosteroid use can lead to adverse cutaneous effects, including facial telangiectasia and acne vulgaris. While medical management often addresses active acne, residual telangiectasia and post-inflammatory erythema (PIE) frequently persist as challenging cosmetic concerns.

AIM

To study the efficacy of intense pulsed light (IPL) in treating facial telangiectasia and PIE in patients with SLE; to record the possible adverse reactions of this treatment.

METHODS

We present a case of a 21-year-old female SLE patient with facial telangiectasia and PIE. The treatment protocol incorporated five sessions of IPL therapy using dual-band vascular filters (530-650 nm and 900-1200 nm) along with a 590 nm filter.

RESULTS

After five sessions of IPL treatment, the facial telangiectasia and PIE of the patient were improved. During the 6-month follow-up period, no adverse reactions and worsening of SLE were observed.

CONCLUSIONS

Low-energy IPL may be a safe and effective therapeutic option for managing steroid-induced telangiectasia and acne-related PIE in SLE patients.

摘要

背景

系统性红斑狼疮(SLE)是一种慢性多系统自身免疫性疾病。标准治疗通常包括使用皮质类固醇、抗疟药和免疫抑制剂;然而,长期使用皮质类固醇会导致不良皮肤反应,包括面部毛细血管扩张和寻常痤疮。虽然药物治疗通常能解决活动性痤疮问题,但残留的毛细血管扩张和炎症后红斑(PIE)常常持续存在,成为具有挑战性的美容问题。

目的

研究强脉冲光(IPL)治疗SLE患者面部毛细血管扩张和PIE的疗效;记录该治疗可能的不良反应。

方法

我们报告一例21岁女性SLE患者,伴有面部毛细血管扩张和PIE。治疗方案包括使用双波段血管滤光片(530 - 650nm和900 - 1200nm)以及590nm滤光片进行五疗程的IPL治疗。

结果

经过五疗程的IPL治疗后,患者的面部毛细血管扩张和PIE得到改善。在6个月的随访期内,未观察到不良反应和SLE病情恶化。

结论

低能量IPL可能是治疗SLE患者类固醇诱导的毛细血管扩张和痤疮相关PIE的一种安全有效的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c0/12371773/20072d98a8bc/JOCD-24-e70389-g001.jpg

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