Li Zhen, Lu Jiejie, Wu Miaoting
Plastic and Cosmetic Center, The Fifth People's Hospital of Hainan Province, Haikou, Hainan Province, China.
J Cosmet Dermatol. 2025 Aug;24(8):e70389. doi: 10.1111/jocd.70389.
Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease. Standard treatment typically involves corticosteroids, antimalarials, and immunosuppressants; however, long-term corticosteroid use can lead to adverse cutaneous effects, including facial telangiectasia and acne vulgaris. While medical management often addresses active acne, residual telangiectasia and post-inflammatory erythema (PIE) frequently persist as challenging cosmetic concerns.
To study the efficacy of intense pulsed light (IPL) in treating facial telangiectasia and PIE in patients with SLE; to record the possible adverse reactions of this treatment.
We present a case of a 21-year-old female SLE patient with facial telangiectasia and PIE. The treatment protocol incorporated five sessions of IPL therapy using dual-band vascular filters (530-650 nm and 900-1200 nm) along with a 590 nm filter.
After five sessions of IPL treatment, the facial telangiectasia and PIE of the patient were improved. During the 6-month follow-up period, no adverse reactions and worsening of SLE were observed.
Low-energy IPL may be a safe and effective therapeutic option for managing steroid-induced telangiectasia and acne-related PIE in SLE patients.
系统性红斑狼疮(SLE)是一种慢性多系统自身免疫性疾病。标准治疗通常包括使用皮质类固醇、抗疟药和免疫抑制剂;然而,长期使用皮质类固醇会导致不良皮肤反应,包括面部毛细血管扩张和寻常痤疮。虽然药物治疗通常能解决活动性痤疮问题,但残留的毛细血管扩张和炎症后红斑(PIE)常常持续存在,成为具有挑战性的美容问题。
研究强脉冲光(IPL)治疗SLE患者面部毛细血管扩张和PIE的疗效;记录该治疗可能的不良反应。
我们报告一例21岁女性SLE患者,伴有面部毛细血管扩张和PIE。治疗方案包括使用双波段血管滤光片(530 - 650nm和900 - 1200nm)以及590nm滤光片进行五疗程的IPL治疗。
经过五疗程的IPL治疗后,患者的面部毛细血管扩张和PIE得到改善。在6个月的随访期内,未观察到不良反应和SLE病情恶化。
低能量IPL可能是治疗SLE患者类固醇诱导的毛细血管扩张和痤疮相关PIE的一种安全有效的治疗选择。