Ventre J
Behav Brain Res. 1985 Oct;17(3):221-34. doi: 10.1016/0166-4328(85)90046-4.
The cortical control of the vestibulo-ocular reflex (VOR) and visual suppression of VOR was studied in 13 adult cats with unilateral lesions. VOR was tested in the dark by sinusoidal rotations of the animal at different frequencies. Visual suppression of VOR was tested in the light by keeping the visual field stationary with respect to the animal. No deficits of VOR and visual suppression of VOR appeared following unilateral ablations of visual cortex. Unilateral lesions of different parts of the suprasylvian cortex were made in the posterior and middle suprasylvian cortex involving area 7 and the lateral suprasylvian area (LSA). After middle suprasylvian cortex damage (particularly area 7), all the animals exhibited a VOR asymmetry due mainly to a gain decrease of slow phases directed towards the side of the lesion. In two animals, transitory spontaneous nystagmus was present in the dark with the fast phase directed toward the side of the lesion. Only when LSA was destroyed, could an asymmetry of the visual suppression of VOR be observed with a loss of the visual suppression during ipsilateral rotations. The VOR deficit was transient: spontaneous nystagmus disappeared within the first postoperative week, the vestibular asymmetry and the loss of visual suppression of VOR were no longer present after 2-3 weeks. We conclude that the middle suprasylvian cortex, particularly area 7, exerts an ipsilateral control on the VOR.
在13只患有单侧损伤的成年猫中，研究了前庭眼反射（VOR）的皮质控制以及VOR的视觉抑制。在黑暗中，通过以不同频率对动物进行正弦旋转来测试VOR。在光照下，通过使视野相对于动物保持静止来测试VOR的视觉抑制。单侧切除视觉皮层后，未出现VOR及VOR视觉抑制的缺陷。在颞上回后部和中部进行不同部位的单侧损伤，涉及7区和颞上外侧区（LSA）。颞上回中部皮质损伤（特别是7区）后，所有动物均表现出VOR不对称，主要是由于指向损伤侧的慢相增益降低。在两只动物中，黑暗中出现了短暂的自发性眼球震颤，快相指向损伤侧。只有当LSA被破坏时，才能观察到VOR视觉抑制的不对称，同侧旋转时视觉抑制丧失。VOR缺陷是短暂的：自发性眼球震颤在术后第一周内消失，2-3周后前庭不对称和VOR视觉抑制丧失不再存在。我们得出结论，颞上回中部皮质，特别是7区，对VOR施加同侧控制。
