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猴子顶叶后部(7区)病变对前庭眼反射的影响。

Effects of posterior parietal lesions (area 7) on VOR in monkeys.

作者信息

Ventre J, Faugier-Grimaud S

出版信息

Exp Brain Res. 1986;62(3):654-8. doi: 10.1007/BF00236046.

DOI:10.1007/BF00236046
PMID:3487465
Abstract

Unilateral ablations of area 7 were performed in three adult monkeys. Vestibulo-ocular reflex (VOR) was tested in the dark by sinusoidal rotations at different frequencies. Following lesion of area 7, spontaneous nystagmus was observed in the dark, with the fast phase directed toward the lesioned side. The same lesion induced a strong VOR asymmetry due to a gain decrease when the animal was rotated toward the side contralateral to the lesion and an increase when rotated toward the opposite side. These VOR deficits were transient: spontaneous nystagmus was no longer present after the first post-operative week whereas the VOR asymmetry lasted for 2 to 4 weeks after the lesion. It is concluded that area 7 might be involved in an ipsilateral control of the slow component of VOR. These results support the idea that posterior parietal cortex plays a role in body reference stabilization.

摘要

对三只成年猴子进行了单侧7区切除。通过在黑暗中以不同频率进行正弦旋转来测试前庭眼反射(VOR)。在7区受损后,在黑暗中观察到自发性眼球震颤,快相指向受损侧。由于动物向病变对侧旋转时增益降低,而向相反侧旋转时增益增加,相同的病变导致了强烈的VOR不对称。这些VOR缺陷是短暂的:术后第一周后不再出现自发性眼球震颤,而VOR不对称在病变后持续2至4周。得出的结论是,7区可能参与了VOR慢相的同侧控制。这些结果支持了后顶叶皮质在身体参考稳定中起作用的观点。

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