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尼日尔三角洲地区油气污染社区高血压患病率与心电图左心室肥厚的比较研究

A Comparative Study of the Prevalence of Hypertension and Electrocardiographic Left Ventricular Hypertrophy in Oil-and Gas-Polluted Communities in the Niger Delta Region.

作者信息

Mankwe A C, Ugwu T C, Aprioku J S, Obianime A W

机构信息

Division of Cardiology, Department of Internal Medicine, Federal Medical Centre, Yenagoa. Email: chesamankweatyahoo.com, Phone: +234 (0) 8035021282.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Madonna University, Elele, Rivers State, Nigeria.

出版信息

West Afr J Med. 2025 Mar 31;42(3):190-201.

Abstract

BACKGROUND

Hypertension with its associated sequelae is the most important risk factor for cardiovascular disease and the leading cause of mortality worldwide. The multifactorial associations of environmental influence on blood pressure seem to play a key role in the etiopathogenesis of hypertension and should be more intently investigated.

OBJECTIVE

This study evaluated the prevalence of hypertension and electrocardiographic left ventricular hypertrophy of residents in three oil producing (exposed) communities in Rivers State (Mbodo-Aluu, K-Dere and Engeni) and a non-oil producing (control) community in Anambra State (Mgbeke-Uli).

METHODS

A total of 570 subjects were recruited for this study. Sociodemographic, anthropometric, electrocardiographic parameters, and blood pressure were obtained from the subjects in a standardized manner.

RESULTS

Showed that the mean value of the systolic and diastolic blood pressures of subjects in the exposed communities were higher (p<0.001) than those of the controls. Furthermore, the prevalence of hypertension and left ventricular hypertrophy in exposed communities were higher (p<0.001) when compared with the control.

摘要

背景

高血压及其相关后遗症是心血管疾病最重要的危险因素,也是全球死亡的主要原因。环境因素对血压的多因素关联似乎在高血压的发病机制中起关键作用,应更深入地进行研究。

目的

本研究评估了河流州三个产油(暴露)社区(姆博多-阿鲁、K-德雷和恩杰尼)以及阿南布拉州一个非产油(对照)社区(姆贝凯-乌利)居民的高血压患病率和心电图左心室肥厚情况。

方法

本研究共招募了570名受试者。以标准化方式从受试者处获取社会人口统计学、人体测量学、心电图参数和血压数据。

结果

显示暴露社区受试者的收缩压和舒张压平均值高于对照组(p<0.001)。此外,与对照组相比,暴露社区的高血压患病率和左心室肥厚患病率更高(p<0.001)。

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