Terada N, Yamane T, Matsumoto K, Asai H, Kitamura Y
Biol Reprod. 1985 Nov;33(4):899-901. doi: 10.1095/biolreprod33.4.899.
The role of mast cells in induction of uterine eosinophilia was investigated by using genetically mast cell-deficient (WB X C57BL/6)F1-W/Wv (hereafter called WBB6F1-W/Wv) mice. The injection of estradiol-17 beta (0.16 micrograms/g body weight) increased the peroxidase activity and eosinophil number in the uteri of castrated WBB6F1-W/Wv and WBB6F1-+/+ mice. Since no significant differences were detectable between these two type of mice, mast cells did not seem to be essential for the estrogen-induced uterine eosinophilia, at least in mice.
通过使用基因性肥大细胞缺陷的（WB×C57BL/6）F1-W/Wv（以下称为WBB6F1-W/Wv）小鼠，研究了肥大细胞在诱导子宫嗜酸性粒细胞增多中的作用。注射17β-雌二醇（0.16微克/克体重）可增加去势的WBB6F1-W/Wv和WBB6F1-+/+小鼠子宫中的过氧化物酶活性和嗜酸性粒细胞数量。由于在这两种类型的小鼠之间未检测到显著差异，因此至少在小鼠中，肥大细胞似乎对于雌激素诱导的子宫嗜酸性粒细胞增多不是必需的。
