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局部创伤的猴脑的血流与氧消耗

Blood flow and oxygen consumption of the focally traumatized monkey brain.

作者信息

Martins A N, Doyle T F

出版信息

J Neurosurg. 1977 Sep;47(3):346-52. doi: 10.3171/jns.1977.47.3.0346.

DOI:10.3171/jns.1977.47.3.0346
PMID:408466
Abstract

The exposed left superior frontal gyrus of the anesthetized macaque brain was focally traumatized by a jet of compressed air. Focal blood flow in tissue around the lesion and total cerebral blood flow was determined before and during the 4 hours after trauma by the hydrogen clearance technique. Blood flow fell in tissue adjacent to the injured brain but the reduction was not statistically significant. Total cerebral blood flow, blood flow in the right superior-frontal gyrus, and oxygen consumption of the brain was unaffected by the trauma. The authors conclude that neither spreading ischemia within uninjured tissue surrounding focally traumatized brain nor posttraumatic diaschisis is readily provoked in the anesthetized brain of the monkey.

摘要

对麻醉的猕猴大脑暴露的左额上回进行局部压缩空气喷射创伤。在创伤前和创伤后4小时内,采用氢清除技术测定损伤周围组织的局部血流和全脑血流量。损伤脑邻近组织的血流下降,但下降无统计学意义。创伤对全脑血流量、右额上回血流及脑氧耗无影响。作者得出结论,在麻醉的猕猴大脑中,局灶性创伤性脑周围未损伤组织内的扩散性缺血和创伤后远隔性机能障碍均不易诱发。

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