Jacques L, Mathieu D, Mathé G
Biomed Pharmacother. 1985;39(6):314-25.
Admission to hospital considerably increases the risk of cross infection. The sources of contamination are of exogenous origin (airborne flora) or endogenous (intestinal flora). Because of the great susceptibility of immunosuppressed patients to microbial agents, it is essential to treat them in a special environment in which there is rigorous attention to hygiene and asepsis. In order to ensure these optimal conditions have been attained, we have made a bacteriological survey for several months in the Service des Maladies Sanguines et Tumorales of the Paul Brousse Hospital, Villejuif. The first part of the survey has given an assessment of the efficiency of the positive pressure air filtration system in one of the units on the Service. Although it should not be neglected, the airborne microbial flora appears to have only a slight effect on the development of infections in our patients. By contrast, the endogenous flora is the main source of infection. Apart from infection via intravenous drips, it is essentially transmitted by direct contact with the nurses' hands or via a variety of instruments. On account of its importance the direct transmission will be described in the second part of this report.
住院会显著增加交叉感染的风险。污染源有外源性(空气传播菌群)和内源性(肠道菌群)。由于免疫抑制患者对微生物制剂非常敏感,在一个严格注重卫生和无菌的特殊环境中对他们进行治疗至关重要。为了确保达到这些最佳条件,我们在维勒瑞夫市保罗·布劳斯医院的血液和肿瘤疾病科进行了为期数月的细菌学调查。调查的第一部分对该科室其中一个单元的正压空气过滤系统的效率进行了评估。尽管空气传播的微生物菌群不应被忽视,但它对我们患者感染的发展似乎只有轻微影响。相比之下,内源性菌群是主要感染源。除了通过静脉滴注感染外,它主要通过直接接触护士的手或通过各种器械传播。鉴于其重要性,直接传播将在本报告的第二部分进行描述。