Mahdjoub Tarik, Michot Nicolas, Karam Elias, Verger Martine Le, Giger-Pabst Urs, Ouaïssi Mehdi
Department of Digestive, Oncological, Endocrine, Hepatobiliary and Liver Transplant, Unité de Chirurgie Colo-rectale, Trousseau Hospital, University Hospital of Tours, Avenue de la République, Chambray- Les-Tours, France.
Pharmacy, CHU de Tours-Trousseau, Avenue de la République, Chambray- Les-Tours, France.
BMC Surg. 2025 Aug 22;25(1):383. doi: 10.1186/s12893-025-03139-6.
The objective of this study is to compare the perioperative clinical outcomes between power-assisted circular staplers (PCS) and manually-operated circular staplers (MCS) with directional stapling technology (DST) for deep colorectal anastomoses.
A retrospective analysis of a prospective database of 64 consecutive patients who underwent elective surgery for low colorectal anastomosis (< 7 cm from the anal verge) between February 2020 and December 2022 at a tertiary referral center for colorectal surgery at the University Hospital of Tours, France. Patients were divided into two groups according to the stapler used: PCS group II; (n = 35) and MCS (group I; n = 29). Data collected included demographic characteristics, intraoperative parameters, postoperative complications (Dindo-Clavien), and oncological outcomes.
The PCS group had significantly lower overall rates of postoperative complications compared to the MCS group (31.4% vs. 62%, p = 0.022). In particular, anastomotic bleeding (AB) was less frequent in the PCS group (0% vs. 17.2%, p = 0.015). While no significant differences in recurrence or survival events were observed between groups during follow-up, the PCS group demonstrated a lower incidence of symptomatic anastomotic leaks (8.6% vs.13.6%, p = 0.069) and postoperative ileus (0% vs. 20.7%, p = 0.025).
In our study, the use of PCS for deep rectal anastomosis was associated with a significantly lower overall postoperative complication rate, rate of symptomatic anastomotic leackage (AL) and AB. Our data support the potential preferential use of PCS in clinical practice. However, larger prospective randomized trials should be conducted to further investigate the potential clinical benefits and cost-effectiveness of using PCS in selected patient populations.
本研究的目的是比较电动圆形吻合器(PCS)和采用定向吻合技术(DST)的手动圆形吻合器(MCS)在低位结直肠吻合术中的围手术期临床结果。
对法国图尔大学医院结直肠外科三级转诊中心2020年2月至2022年12月期间连续64例行低位结直肠吻合术(距肛缘<7cm)择期手术患者的前瞻性数据库进行回顾性分析。根据所使用的吻合器将患者分为两组:PCS组(n = 35)和MCS组(I组;n = 29)。收集的数据包括人口统计学特征、术中参数、术后并发症(Dindo-Clavien分级)和肿瘤学结果。
与MCS组相比,PCS组术后总体并发症发生率显著更低(31.4%对62%,p = 0.022)。特别是,PCS组吻合口出血(AB)的发生率更低(0%对17.2%,p = 0.015)。虽然随访期间两组之间在复发或生存事件方面未观察到显著差异,但PCS组有症状的吻合口漏发生率更低(8.6%对13.6%,p = 0.069),术后肠梗阻发生率也更低(0%对20.7%,p = 0.025)。
在我们的研究中,使用PCS进行低位直肠吻合术与术后总体并发症发生率、有症状的吻合口漏(AL)发生率和AB发生率显著更低相关。我们的数据支持在临床实践中优先使用PCS。然而,应进行更大规模的前瞻性随机试验,以进一步研究在特定患者群体中使用PCS的潜在临床益处和成本效益。